Fetomaternal immune cross-talk and its consequences for maternal and offspring's health

PC Arck, K Hecher - Nature medicine, 2013 - nature.com
An improved mechanistic understanding of the adaptational processes mounted during
mammalian reproduction is emerging. Intricate pathways occurring at the fetomaternal …

The placenta in toxicology. Part II: Systemic and local immune adaptations in pregnancy

J Svensson-Arvelund, J Ernerudh… - Toxicologic …, 2014 - journals.sagepub.com
During pregnancy, the maternal immune system is challenged by the semiallogeneic fetus,
which must be tolerated without compromising fetal or maternal health. This review updates …

Histology atlas of the developing mouse placenta

SA Elmore, RZ Cochran, B Bolon… - Toxicologic …, 2022 - journals.sagepub.com
The use of the mouse as a model organism is common in translational research. This mouse–
human similarity holds true for placental development as well. Proper formation of the …

Pregnancy and spontaneous fetal loss: A pig perspective

M Bidarimath, C Tayade - Molecular reproduction and …, 2017 - Wiley Online Library
Pigs have a unique, non‐invasive epitheliochorial placenta where maternal and fetal layers
lay in apposition. Indentation of fetal capillaries into the trophoblasts and maternal …

Defective soil for a fertile seed? Altered endometrial development is detrimental to pregnancy success

J Evans, NJ Hannan, C Hincks, LJF Rombauts… - PloS one, 2012 - journals.plos.org
Background Synchronous development of the endometrium (to achieve a receptive state)
and of the embryo is essential for successful implantation and ongoing pregnancy …

Pro-and anti-inflammatory cytokines in the first trimester—comparison of missed miscarriage and normal pregnancy

M Kwiatek, T Gęca, A Kwaśniewska - International Journal of …, 2021 - mdpi.com
The advantage in response of Th2 over Th1 is observed in normal pregnancy in peripheral
blood. A disturbance of this balance can lead to symptoms of miscarriage and pregnancy …

[HTML][HTML] Immunologic challenges of human reproduction: an evolving story

KJ Hyde, DJ Schust - Fertility and Sterility, 2016 - Elsevier
Characterization of the implanting human fetus as an allograft prompted a field of research
in reproductive immunology that continues to fascinate and perplex scientists. Paternal-or …

Insights into extracellular vesicle/exosome and miRNA mediated Bi-directional communication during porcine pregnancy

M Bidarimath, H Lingegowda, JE Miller… - Frontiers in Veterinary …, 2021 - frontiersin.org
Spontaneous fetal loss is one of the most important challenges that commercial pig industry
is still facing in North America. Research over the decade provided significant insights into …

Altered thermal behavior of blood plasma proteome related to inflammatory cytokines in early pregnancy loss

R Komsa-Penkova, A Danailova, S Krumova… - International Journal of …, 2022 - mdpi.com
Early pregnancy loss (EPL) is a relatively common pathology of which almost 50% of cases
remain idiopathic. In the search for novel biomarkers, differential scanning calorimetry (DSC) …

An immunological basis for chronic histiocytic intervillositis in recurrent fetal loss

AD Reus, NM van Besouw… - American Journal of …, 2013 - Wiley Online Library
Problem Chronic histiocytic intervillositis (CHIV) is a rare type of placental pathology that is
associated with reproductive loss at all gestational ages. The aim of the study was to …