Proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors are a novel group of
hypolipidemic drugs that are recommended particularly for high-risk hypercholesterolemia …

Hypertension is one of the most common and complicated disorders associated with genetic
and environmental risk factors. The angiotensin-converting enzyme (ACE) is important in the …

A cluster of three genes CELSR2, PSRC1, and SORT1 has been associated with
cardiovascular diseases. Thus, the aim of this study was (i) to perform a systematic review …

Cardiovascular diseases are among the leading causes of death worldwide. Many of those
diseases require treatment with warfarin, an anticoagulant that has a large high inter and …

Background: Polymorphisms in the CYP2C9, VKORC1, MDR1 and APOE genes may impact
warfarin dose. Aim: To investigate the influence of sociodemographic, clinical factors and …

Ketosis is a metabolic disease that often occurs in dairy cows postpartum and is a result of
disordered lipid metabolism. Acetyl-coenzyme A (CoA) acetyltransferase 2 (ACAT2) is …

Aims This study aims to investigate the influence of MEF2A and SLC22A3-LPAL2-LPA
polymorphisms on cardiovascular disease susceptibility and responsiveness to warfarin …

Background High blood pressure, also known as hypertension (HTN), is a complicated
disorder that is controlled by a complex network of physiological processes. Untreated …

Introduction Warfarin has been in use for more than 60 years; however, it has serious side
effects including major bleeding. The high interpatient variability in the required dose …

Abstract Objectives: Abdominal Aortic Aneurysm (AAA) is a complex disease with both
genetic and environmental risk factors. This study aimed to examine the potential …