Oral microbiome and SARS-CoV-2: beware of lung co-infection

L Bao, C Zhang, J Dong, L Zhao, Y Li… - Frontiers in microbiology, 2020 - frontiersin.org
The new coronavirus SARS-CoV-2, the cause of COVID-19, has become a public health
emergency of global concern. Like the SARS and influenza pandemics, there have been a …

Periodontitis exacerbates and promotes the progression of chronic kidney disease through oral flora, cytokines, and oxidative stress

L Li, YL Zhang, XY Liu, X Meng, RQ Zhao… - Frontiers in …, 2021 - frontiersin.org
Periodontitis is a type of systemic immune inflammation that is caused by the complex
infection of a variety of microorganisms in the subgingival plaque and the imbalance of the …

[HTML][HTML] Macrophages in periodontitis: a dynamic shift between tissue destruction and repair

L Yin, X Li, J Hou - Japanese Dental Science Review, 2022 - Elsevier
Periodontitis is a chronic inflammatory disease associated with a dysbiotic bacterial biofilm
in the subgingival environment that may disturb the balance between the oral microbiome …

The Th17/Treg cell balance: crosstalk among the immune system, bone and microbes in periodontitis

J Deng, C Lu, Q Zhao, K Chen, S Ma… - Journal of periodontal …, 2022 - Wiley Online Library
Periodontopathic bacteria constantly stimulate the host, which causes an immune response,
leading to host‐induced periodontal tissue damage. The complex interaction and imbalance …

Porphyromonas gingivalis, a Long-Range Pathogen: Systemic Impact and Therapeutic Implications

H Mulhall, O Huck, S Amar - Microorganisms, 2020 - mdpi.com
Periodontitis is an inflammatory disease associated with a dysbiosis of the oral flora
characterized by a chronic sustained inflammation leading to destruction of tooth-supporting …

Association between periodontitis and inflammatory comorbidities: The common role of innate immune cells, underlying mechanisms and therapeutic targets

Q Wu, W Zhang, Y Lu, H Li, Y Yang, F Geng… - International …, 2024 - Elsevier
Periodontitis, which is related to various systemic diseases, is a chronic inflammatory
disease caused by periodontal dysbiosis of the microbiota. Multiple factors can influence the …

Resveratrol Inhibits MMP3 and MMP9 Expression and Secretion by Suppressing TLR4/NF‐κB/STAT3 Activation in Ox‐LDL‐Treated HUVECs

M Zhang, Y Xue, H Chen, L Meng… - Oxidative medicine …, 2019 - Wiley Online Library
Aim. Resveratrol is a natural plant polyphenol. The present study investigated the effects of
resveratrol on the Toll‐like receptor 4‐(TLR4‐) mediated expression and secretion of matrix …

Periodontopathic Microbiota and Atherosclerosis: Roles of TLR‐Mediated Inflammation Response

Y Zou, Y Huang, S Liu, J Yang, W Zheng… - Oxidative Medicine …, 2022 - Wiley Online Library
Atherosclerosis is a chronic inflammatory disease with a high prevalence worldwide,
contributing to a series of adverse cardiovascular and cerebrovascular diseases …

Akt2 affects periodontal inflammation via altering the M1/M2 ratio

X Wu, H Chen, Y Wang, Y Gu - Journal of Dental Research, 2020 - journals.sagepub.com
Periodontitis is a bacteria-driven inflammatory destructive disease that leads to attachment
loss, bone resorption, and even tooth loss. Accumulating studies revealed that macrophages …

Can metagenomics unravel the impact of oral bacteriome in human diseases?

I Chattopadhyay, W Lu, R Manikam… - Biotechnology and …, 2023 - Taylor & Francis
Oral microbial ecosystems are vital in maintaining the health of the oral cavity and the entire
body. Oral microbiota is associated with the progression of oral diseases such as dental …