Fluorescent functional nucleic acid: Principles, properties and applications in bioanalyzing

XX Wang, LJ Zhu, ST Li, YZ Zhang, SY Liu… - TrAC Trends in …, 2021 - Elsevier
Functional nucleic acids with fluorescence properties are powerful research tools for both
biomolecular analysis and biological nanomaterials. This review collected these interesting …

Fluorescent nucleoside analogs: probes for investigating nucleic acid structure and function

AA Tanpure, MG Pawar… - Israel Journal of …, 2013 - Wiley Online Library
Base‐modified fluorescent nucleoside analog probes have been very valuable in the study
of nucleic acid structure and function. Many of them structurally resemble natural bases, and …

Small molecule–RNA targeting: starting with the fundamentals

AE Hargrove - Chemical Communications, 2020 - pubs.rsc.org
The structural and regulatory elements in therapeutically relevant RNAs offer many
opportunities for targeting by small molecules, yet fundamental understanding of what drives …

Microenvironment-sensitive fluorescent nucleotide probes from benzofuran, benzothiophene, and selenophene as substrates for DNA polymerases

P Ghosh, HM Kropp, K Betz, S Ludmann… - Journal of the …, 2022 - ACS Publications
DNA polymerases can process a wide variety of structurally diverse nucleotide substrates,
but the molecular basis by which the analogs are processed is not completely understood …

Conformation-sensitive nucleoside analogues as topology-specific fluorescence turn-on probes for DNA and RNA G-quadruplexes

AA Tanpure, SG Srivatsan - Nucleic acids research, 2015 - academic.oup.com
Abstract Development of probes that can discriminate G-quadruplex (GQ) structures and
indentify efficient GQ binders on the basis of topology and nucleic acid type is highly desired …

Small molecule-based pattern recognition to classify RNA structure

CS Eubanks, JE Forte, GJ Kapral… - Journal of the American …, 2017 - ACS Publications
Three-dimensional RNA structures are notoriously difficult to determine, and the link
between secondary structure and RNA conformation is only beginning to be understood …

Polymerase synthesis of DNA labelled with benzylidene cyanoacetamide-based fluorescent molecular rotors: fluorescent light-up probes for DNA-binding proteins

D Dziuba, R Pohl, M Hocek - Chemical Communications, 2015 - pubs.rsc.org
Viscosity-sensitive fluorophores, fluorescent molecular rotors based on aminobenzylidene–
cyanoacetamide moiety, were tethered to 2′-deoxycytidine triphosphate via a …

Theoretical study on fluorescent T-analogues for selective recognition of 2-aminoadenine (Z) in aqueous solution via base-pair induced ESICT mechanism

X Zhang, L Duan, Y Zhao, Y Zhang, Q Meng… - Journal of Molecular …, 2023 - Elsevier
Abstract The unusual 2-aminoadenine (Z), a fairly exceptional base that is different from four
types of normal nucleobases (ATCG), has also been detected in carbon-rich meteorites and …

Isomorphic fluorescent nucleosides facilitate real‐time monitoring of RNA depurination by ribosome inactivating proteins

D Cong, Y Li, PT Ludford III, Y Tor - Chemistry–A European …, 2022 - Wiley Online Library
Ribosome‐inactivating proteins, a family of highly cytotoxic proteins, interfere with protein
synthesis by depurinating a specific adenosine residue within the conserved α‐sarcin/ricin …

Hierarchical self-assembly of switchable nucleolipid supramolecular gels based on environmentally-sensitive fluorescent nucleoside analogs

A Nuthanakanti, SG Srivatsan - Nanoscale, 2016 - pubs.rsc.org
Exquisite recognition and folding properties have rendered nucleic acids as useful
supramolecular synthons for the construction of programmable architectures. Despite their …