MicroRNA alteration, application as biomarkers, and therapeutic approaches in neurodegenerative diseases

TPN Nguyen, M Kumar, E Fedele, G Bonanno… - International journal of …, 2022 - mdpi.com
MicroRNAs (miRNAs) are essential post-transcriptional gene regulators involved in various
neuronal and non-neuronal cell functions and play a key role in pathological conditions …

What are the key gut microbiota involved in neurological diseases? A systematic review

B Bonnechère, N Amin, C van Duijn - International Journal of Molecular …, 2022 - mdpi.com
There is a growing body of evidence highlighting there are significant changes in the gut
microbiota composition and relative abundance in various neurological disorders. We …

Nanophytomedicines as therapeutic agents for Parkinson's Disease

J Burns, AC Buck, S D'Souza, A Dube, S Bardien - ACS omega, 2023 - ACS Publications
Phytochemicals are promising therapeutics for various neurodegenerative disorders,
including Parkinson's disease (PD). However, their efficacy, pharmacokinetic properties, and …

Network pharmacology analysis of the active ingredients of Corydalis hendersonii Hemsl. and their effects on eliminating neuroinflammation and improving motor …

J Wang, QT Liu, DY Shen, JP Bai, Y Hu… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Corydalis hendersonii Hemsl.(CH), is a traditional
Tibetan medicine used in highland areas for the treatment of alpine polycythemia, ulcers …

[HTML][HTML] The neuroprotective effect of quercetin nanoparticles in the therapy of neuronal damage stimulated by acrolein

SM Sanad, R Farouk, SE Nassar, MY Alshahrani… - Saudi Journal of …, 2023 - Elsevier
A gradual loss of neuronal function or structure causes neurodegenerative disorders such
as Parkinson's and Alzheimer's. Neurological damage might cause cell death. Acrolein is a …

Velvet bean (Mucuna pruriens): A sustainable protein source for tomorrow

C Baby, S Kaur, J Singh, R Prasad - Legume Science, 2023 - Wiley Online Library
Protein is one of the essential major nutrients required for the cell functioning in human
body. Complete proteins, which are usually found in animal‐based proteins, despite of …

Invertebrate genetic models of amyotrophic lateral sclerosis

LJ Zhou, RS Xu - Frontiers in Molecular Neuroscience, 2024 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a common adult-onset neurodegenerative disease
characterized by the progressive death of motor neurons in the cerebral cortex, brain stem …

Compound Characterization of a Mucuna Seed Extract: L-Dopa, Arginine, Stizolamine, and Some Fructooligosaccharides

AL Hernández-Orihuela, KV Castro-Cerritos, MG López… - Compounds, 2022 - mdpi.com
Human societies demand sustainable alternatives for goods and services. Plants are
sustainable sources of important metabolites with beneficial impacts on human health …

Neuroprotective microRNA-381 Binds to Repressed Early Growth Response 1 (EGR1) and Alleviates Oxidative Stress Injury in Parkinson's Disease

S Guo, Y Gao, Y Zhao - ACS Chemical Neuroscience, 2023 - ACS Publications
As a common and disabling disease of the elderly, the standard therapies of Parkinson's
disease (PD) fail to curb the ongoing neurodegeneration, thus calling for newer strategies …

[HTML][HTML] Effect of Mucuna pruriens seed extract on depression-like behavior derived from mild traumatic brain injury in rats

A Mata-Bermudez, R Trejo-Chávez… - …, 2024 - pmc.ncbi.nlm.nih.gov
Background Traumatic brain injury (TBI) is a severe health problem for which there is no
specific treatment, leading to neurological or neuropsychological consequences. One of the …