Nonalcoholic fatty liver disease (NAFLD) is a global public health concern. Its natural history,
the development of nonalcoholic steatohepatitis (NASH) and fibrosis, is highly variable …

Effective immunosupression management is central to achieving optimal outcomes in liver
transplant recipients. Current immunosuppression regimens and agents are highly effective …

The increasing potency of immunosuppression (IS) agents resulted in significantly
decreased rates of steroid resistant rejection and rejection related graft loss in liver …

Since the implementation of the Model of End-stage Liver Disease score-based allocation
system, the number of transplant candidates with impaired renal function has increased. The …

Background and Aims Although terlipressin and albumin are effective at treating acute
kidney injury‐hepatorenal syndrome (AKI‐HRS), liver transplantation (LT) is the best …

Donor-derived cell-free DNA (dd-cfDNA) has been evaluated as a rejection marker in organ
transplantation. This study sought to assess the utility of dd-cfDNA to diagnose graft injury in …

Hepatorenal syndrome (HRS), a progressive but potentially reversible deterioration of
kidney function, remains a major complication in patients with advanced cirrhosis, often …

After solid organ transplantation the cornerstone of immunosuppression is based on
calcineurin inhibitors (CNIs), mostly tacrolimus. However, CNIs have a very narrow …

While advances in immunosuppressive therapy have lowered the rate of acute rejection
following liver transplantation, the consequence has been an increase in morbidity and …

Histone deacetylase 6 (HDAC6) uniquely serves as a tumor suppressor in hepatocellular
carcinogenesis, but the underlying mechanisms leading to tumor suppression are not fully …