[HTML][HTML] Proliferative markers as prognostic and predictive tools in early breast cancer: where are we now?
M Colozza, E Azambuja, F Cardoso, C Sotiriou… - Annals of oncology, 2005 - Elsevier
In the last few decades, proliferative markers have been broadly evaluated as prognostic
and predictive factors for early stage breast cancer patients. Several papers evaluating one …
and predictive factors for early stage breast cancer patients. Several papers evaluating one …
MRI radiogenomics for intelligent diagnosis of breast tumors and accurate prediction of neoadjuvant chemotherapy responses-a review
Background and objective This paper aims to overview multidimensional mining algorithms
in relation to Magnetic Resonance Imaging (MRI) radiogenomics for computer aided …
in relation to Magnetic Resonance Imaging (MRI) radiogenomics for computer aided …
Ki-67 as a prognostic marker according to breast cancer subtype and a predictor of recurrence time in primary breast cancer
R Nishimura, T Osako, Y Okumura… - Experimental and …, 2010 - spandidos-publications.com
The choice of adjuvant systemic therapy is based on targeted therapy in line with the St.
Gallen Consensus meeting. In addition to the traditional parameters, the panel …
Gallen Consensus meeting. In addition to the traditional parameters, the panel …
HER2 and TOP2A as predictive markers for anthracycline-containing chemotherapy regimens as adjuvant treatment of breast cancer: a meta-analysis of individual …
Background Prediction of response to anthracycline-based therapy for breast cancer is
challenging. We aimed to assess the value of HER2 and TOP2A as predictive markers of …
challenging. We aimed to assess the value of HER2 and TOP2A as predictive markers of …
Clinical significance of Ki-67 in neoadjuvant chemotherapy for primary breast cancer as a predictor for chemosensitivity and for prognosis
R Nishimura, T Osako, Y Okumura, M Hayashi, N Arima - Breast cancer, 2010 - Springer
Background Neoadjuvant chemotherapy (NAC) is one of the main strategies for patients with
locally advanced breast cancer. In recent years several biological markers such as estrogen …
locally advanced breast cancer. In recent years several biological markers such as estrogen …
ERBB2 and TOP2A in breast cancer: a comprehensive analysis of gene amplification, RNA levels, and protein expression and their influence on prognosis and …
JC Brase, M Schmidt, T Fischbach, H Sültmann… - Clinical Cancer …, 2010 - AACR
Purpose: The prognostic and predictive relevance of epidermal growth factor receptor 2
(ERBB2) and topoisomerase II α (TOP2A) have long been a matter of debate. However, the …
(ERBB2) and topoisomerase II α (TOP2A) have long been a matter of debate. However, the …
Prognostication of prostate cancer based on TOP2A protein and gene assessment: TOP2A in prostate cancer
MF De Resende, S Vieira, LTD Chinen… - Journal of translational …, 2013 - Springer
Background TOP2A encodes for topoisomerase IIα, a nuclear enzyme that controls DNA
topological structure and cell cycle progression. This enzyme is a marker of cell proliferation …
topological structure and cell cycle progression. This enzyme is a marker of cell proliferation …
Topoisomerase-IIα expression as a predictive marker in a population of advanced breast cancer patients randomly treated either with single-agent doxorubicin or …
Purpose: The predictive value of topoisomerase-IIα (topo-II) has been evaluated in
advanced breast cancer patients randomly treated with single-agent doxorubicin or …
advanced breast cancer patients randomly treated with single-agent doxorubicin or …
Chromogenic and fluorescent in situ hybridization in breast cancer
MBK Lambros, R Natrajan, JS Reis-Filho - Human pathology, 2007 - Elsevier
Fluorescent (FISH) and chromogenic (CISH) in situ hybridization have recently become part
of the diagnostic armamentarium of breast pathologists. HER2 gene testing by FISH and/or …
of the diagnostic armamentarium of breast pathologists. HER2 gene testing by FISH and/or …
Cytotoxicity of a natural anthraquinone (Aloin) against human breast cancer cell lines with and without ErbB-2: Topoisomerase II-alpha coamplification
AY Esmat, C Tomasetto, MC Rio - Cancer biology & therapy, 2006 - Taylor & Francis
In the present study the cytotoxic activity of aloin, a natural anthracycline from Aloe plant, is
reported against two human breast cancer cell lines; without (MCF-7) and with (SKBR-3) …
reported against two human breast cancer cell lines; without (MCF-7) and with (SKBR-3) …