[HTML][HTML] Emerging concepts in PD-1 checkpoint biology
KE Pauken, JA Torchia, A Chaudhri, AH Sharpe… - Seminars in …, 2021 - Elsevier
The PD-1 pathway is a cornerstone in immune regulation. While the PD-1 pathway has
received considerable attention for its role in contributing to the maintenance of T cell …
received considerable attention for its role in contributing to the maintenance of T cell …
Akt-targeted therapy as a promising strategy to overcome drug resistance in breast cancer–A comprehensive review from chemotherapy to immunotherapy
Breast cancer is the most frequently occurring cancer in women. Chemotherapy in
combination with immunotherapy has been used to treat breast cancer. Atezolizumab …
combination with immunotherapy has been used to treat breast cancer. Atezolizumab …
A Microenvironment Dual‐Responsive Nano‐Drug Equipped with PD‐L1 Blocking Peptide Triggers Immunogenic Pyroptosis for Prostate Cancer Self‐Synergistic …
H Wang, Z Gao, D Jiao, Y Zhang… - Advanced Functional …, 2023 - Wiley Online Library
Induction of immunogenic cell death (ICD) in tumor combined with immune checkpoint
blockade (ICB) therapy is widely developed to improve the efficacy of cancer …
blockade (ICB) therapy is widely developed to improve the efficacy of cancer …
[HTML][HTML] Regulation of PD-L1 expression in cancer and clinical implications in immunotherapy
X Ju, H Zhang, Z Zhou, Q Wang - American journal of cancer …, 2020 - ncbi.nlm.nih.gov
Abstract PD-1/PD-L1 immune checkpoint blockade therapy has become an effective method
for the treatment of cancers in the clinic. It has great clinical advantages and therapeutic …
for the treatment of cancers in the clinic. It has great clinical advantages and therapeutic …
Basis of PD1/PD-L1 therapies
B Seliger - Journal of clinical medicine, 2019 - mdpi.com
It is obvious that tumor cells have developed a number of strategies to escape immune
surveillance including an altered expression of various immune checkpoints, such as the …
surveillance including an altered expression of various immune checkpoints, such as the …
PD-L1 status in breast cancer: Current view and perspectives
S Vranic, FS Cyprian, Z Gatalica, J Palazzo - Seminars in cancer biology, 2021 - Elsevier
Breast cancer was traditionally not considered a particularly immunogenic tumor. However,
recent developments have shown that some aggressive triple-negative breast cancers are …
recent developments have shown that some aggressive triple-negative breast cancers are …
Progression of m6A in the tumor microenvironment: hypoxia, immune and metabolic reprogramming
X Han, Y Zhu, J Ke, Y Zhai, M Huang, X Zhang… - Cell Death …, 2024 - nature.com
Abstract Recently, N6-methyladenosine (m6A) has aroused widespread discussion in the
scientific community as a mode of RNA modification. m6A comprises writers, erasers, and …
scientific community as a mode of RNA modification. m6A comprises writers, erasers, and …
Chemerin reactivates PTEN and suppresses PD-L1 in tumor cells via modulation of a novel CMKLR1-mediated signaling cascade
Purpose: Chemerin (retinoic acid receptor responder 2, RARRES2) is an endogenous
leukocyte chemoattractant that recruits innate immune cells through its receptor, ChemR23 …
leukocyte chemoattractant that recruits innate immune cells through its receptor, ChemR23 …
Relevance function of linc-ROR in the pathogenesis of cancer
W Chen, J Yang, H Fang, L Li, J Sun - Frontiers in Cell and …, 2020 - frontiersin.org
Long non-coding RNAs (lncRNAs) are the key components of non-coding RNAs (ncRNAs)
with a length of 200 nucleotides. They are transcribed from the so-called “dark matter” of the …
with a length of 200 nucleotides. They are transcribed from the so-called “dark matter” of the …
The regulatory role of PDE4B in the progression of inflammatory function study
Y Su, J Ding, F Yang, C He, Y Xu, X Zhu… - Frontiers in …, 2022 - frontiersin.org
Inflammation is a response of the body to external stimuli (eg. chemical irritants, bacteria,
viruses, etc.), and when the stimuli are persistent, they tend to trigger chronic inflammation …
viruses, etc.), and when the stimuli are persistent, they tend to trigger chronic inflammation …