Animals integrate developmental and nutritional signals before committing crucial resources
to growth and reproduction; however, the pathways that perceive and respond to these …

The animal germline lineage needs to be maintained along generations. However, some
Caenorhabditis elegans wild isolates display a mortal germline phenotype, leading to …

Background One-carbon metabolism, which includes the folate and methionine cycles,
involves the transfer of methyl groups which are then utilised as a part of multiple …

A major goal of healthy aging is to prevent declining resilience and increasing frailty, which
are associated with many chronic diseases and deterioration of stress response. Here, we …

The redox reagent dithiothreitol (DTT) causes stress in the endoplasmic reticulum (ER) by
disrupting its oxidative protein folding environment, which results in the accumulation and …

The Caenorhabditis elegans natural microbiota isolates Pseudomonas lurida MYb11 and
Pseudomonas fluorescens MYb115 protect the host against pathogens through distinct …

Organisms utilize sophisticated neurocircuitry to select optimal food sources within their
environment. Methylobacterium is a lifespan-promoting bacterial diet for C. elegans that …

The maintenance of germ cells is critical for the prosperity of offspring. The amount of food
consumption is known to be closely related to reproduction, ie the number of eggs …

The C. elegans natural microbiota isolates Pseudomonas lurida MYb11 and Pseudomonas
fluorescens MYb115 protect the host against pathogens through distinct mechanisms. While …

An organism encounters an extensive range of dietary choices in its niche. The
macronutrient and micronutrient quotients of these diets instruct downstream molecular …