Overcoming the blood–brain barrier: the role of nanomaterials in treating neurological diseases

D Furtado, M Björnmalm, S Ayton, AI Bush… - Advanced …, 2018 - Wiley Online Library
Therapies directed toward the central nervous system remain difficult to translate into
improved clinical outcomes. This is largely due to the blood–brain barrier (BBB), arguably …

Alginate nanoparticles for drug delivery and targeting

P Severino, CF da Silva, LN Andrade… - Current …, 2019 - ingentaconnect.com
Nanotechnology refers to the control, manipulation, study and manufacture of structures and
devices at the nanometer size range. The small size, customized surface, improved solubility …

Magnetic nanoparticles: preparation, physical properties, and applications in biomedicine

A Akbarzadeh, M Samiei, S Davaran - Nanoscale research letters, 2012 - Springer
Finally, we have addressed some relevant findings on the importance of having well-defined
synthetic strategies developed for the generation of MNPs, with a focus on particle formation …

Modern methods for delivery of drugs across the blood–brain barrier

Y Chen, L Liu - Advanced drug delivery reviews, 2012 - Elsevier
The blood–brain barrier (BBB) is a highly regulated and efficient barrier that provides a
sanctuary to the brain. It is designed to regulate brain homeostasis and to permit selective …

Nanoparticle-based targeted drug delivery

R Singh, JW Lillard Jr - Experimental and molecular pathology, 2009 - Elsevier
Nanotechnology could be defined as the technology that has allowed for the control,
manipulation, study, and manufacture of structures and devices in the “nanometer” size …

Nanoparticles-a review

VJ Mohanraj, Y Chen - Tropical journal of pharmaceutical research, 2006 - ajol.info
For the past few decades, there has been a considerable research interest in the area of
drug delivery using particulate delivery systems as carriers for small and large molecules …

Recent developments in ring opening polymerization of lactones for biomedical applications

AC Albertsson, IK Varma - Biomacromolecules, 2003 - ACS Publications
Aliphatic polyesters prepared by ring-opening polymerization of lactones are now used
worldwide as bioresorbabale devices in surgery (orthopaedic devices, sutures, stents, tissue …

A review of the formation and classification of amphiphilic block copolymer nanoparticulate structures: micelles, nanospheres, nanocapsules and polymersomes

K Letchford, H Burt - European journal of pharmaceutics and …, 2007 - Elsevier
Amphiphilic block copolymers are able to form a range of different nanoparticulate
structures. These include micelles, nanospheres, nanocapsules, and polymersomes. This …

PLGA nanoparticles prepared by nanoprecipitation: drug loading and release studies of a water soluble drug

T Govender, S Stolnik, MC Garnett, L Illum… - Journal of controlled …, 1999 - Elsevier
The nanoprecipitation technique for preparation of nanoparticles suffers the drawback of
poor incorporation of water soluble drugs. The aim of this study was therefore to assess …

Pharmacokinetics of curcumin-loaded PLGA and PLGA–PEG blend nanoparticles after oral administration in rats

NM Khalil, TCF do Nascimento, DM Casa… - Colloids and Surfaces B …, 2013 - Elsevier
The aim of this study was to assess the potential of nanoparticles to improve the
pharmacokinetics of curcumin, with a primary goal of enhancing its bioavailability. Polylactic …