A decade of GWAS results in lung cancer
Genome-wide association studies (GWAS) were successful to identify genetic factors
robustly associated with lung cancer. This review aims to synthesize the literature in this field …
robustly associated with lung cancer. This review aims to synthesize the literature in this field …
[HTML][HTML] The RING finger protein family in health and disease
C Cai, YD Tang, J Zhai, C Zheng - Signal transduction and targeted …, 2022 - nature.com
Ubiquitination is a highly conserved and fundamental posttranslational modification (PTM) in
all eukaryotes regulating thousands of proteins. The RING (really interesting new gene) …
all eukaryotes regulating thousands of proteins. The RING (really interesting new gene) …
[HTML][HTML] Exploring market overreaction, investors' sentiments and investment decisions in an emerging stock market
The representative heuristic and overconfidence are cognitive biases that influence the
decisions of the investors in the stock market. Overconfident investors tend to rely on …
decisions of the investors in the stock market. Overconfident investors tend to rely on …
RBR E3 ubiquitin ligases in tumorigenesis
Abstract RING-in-between-RING (RBR) E3 ligases are one class of E3 ligases that is
characterized by the unique RING-HECT hybrid mechanism to function with E2s to transfer …
characterized by the unique RING-HECT hybrid mechanism to function with E2s to transfer …
[HTML][HTML] Germline mutations in DNA repair genes in lung adenocarcinoma
Introduction Although lung cancer is generally thought to be environmentally provoked,
anecdotal familial clustering has been reported, suggesting that there may be genetic …
anecdotal familial clustering has been reported, suggesting that there may be genetic …
Comprehensive molecular characterization of adenoid cystic carcinoma reveals tumor suppressors as novel drivers and prognostic biomarkers
M Persson, MK Andersson, PE Sahlin… - The Journal of …, 2023 - Wiley Online Library
Adenoid cystic carcinoma (ACC) is a MYB‐driven head and neck malignancy with high rates
of local recurrence and distant metastasis and poor long‐term survival. New effective …
of local recurrence and distant metastasis and poor long‐term survival. New effective …
[HTML][HTML] Cell-free DNA and next-generation sequencing in the service of personalized medicine for lung cancer
CW Bennett, G Berchem, YJ Kim, V El-Khoury - Oncotarget, 2016 - ncbi.nlm.nih.gov
Personalized medicine has emerged as the future of cancer care to ensure that patients
receive individualized treatment specific to their needs. In order to provide such care …
receive individualized treatment specific to their needs. In order to provide such care …
Genome-wide association study of familial lung cancer
J Byun, AG Schwartz, C Lusk, AS Wenzlaff… - …, 2018 - academic.oup.com
To identify genetic variation associated with lung cancer risk, we performed a genome-wide
association analysis of 685 lung cancer cases that had a family history of two or more first or …
association analysis of 685 lung cancer cases that had a family history of two or more first or …
Association between Parkinson disease and risk of cancer in Taiwan
PY Lin, SN Chang, TH Hsiao, BT Huang, CH Lin… - JAMA …, 2015 - jamanetwork.com
Importance Parkinson disease (PD) has been reported to be associated with a general
reduced risk of cancer. These studies were mainly carried out in Western populations and …
reduced risk of cancer. These studies were mainly carried out in Western populations and …
[HTML][HTML] The contribution of hereditary cancer-related germline mutations to lung cancer susceptibility
M Liu, X Liu, P Suo, Y Gong, B Qu, X Peng… - Translational Lung …, 2020 - ncbi.nlm.nih.gov
Background Germline variations may contribute to lung cancer susceptibility besides
environmental factors. The influence of germline mutations on lung cancer susceptibility and …
environmental factors. The influence of germline mutations on lung cancer susceptibility and …