Omics of antimicrobials and antimicrobial resistance
VM Chernov, OA Chernova… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: The development of new antimicrobials has become an urgent priority because
of a global challenge emerging from the rise of antimicrobial resistant pathogens. Areas …
of a global challenge emerging from the rise of antimicrobial resistant pathogens. Areas …
Alveolar regeneration in COVID-19 patients: a network perspective
A viral infection involves entry and replication of viral nucleic acid in a host organism,
subsequently leading to biochemical and structural alterations in the host cell. In the case of …
subsequently leading to biochemical and structural alterations in the host cell. In the case of …
Geptop 2.0: an updated, more precise, and faster Geptop server for identification of prokaryotic essential genes
QF Wen, S Liu, C Dong, HX Guo, YZ Gao… - Frontiers in …, 2019 - frontiersin.org
Geptop has performed effectively in the identification of prokaryotic essential genes since its
first release in 2013. It estimates gene essentiality for prokaryotes based on orthology and …
first release in 2013. It estimates gene essentiality for prokaryotes based on orthology and …
Comparative subtractive proteomics based ranking for antibiotic targets against the dirtiest superbug: Acinetobacter baumannii
Multidrug-resistant Acinetobacter baumannii is indeed to be the most successful nosocomial
pathogen responsible for myriad infections in modern health care system. Computational …
pathogen responsible for myriad infections in modern health care system. Computational …
Study of anticancer and antibacterial activities of Foeniculum vulgare, Justicia adhatoda and Urtica dioica as natural curatives
R Batool, H Salahuddin, T Mahmood… - Cellular and Molecular …, 2017 - cellmolbiol.org
High-throughput technologies, such as synthetic biology and genomics have paved new
paths for discovery and utility of medicinally beneficial plants. Bioactive molecules isolated …
paths for discovery and utility of medicinally beneficial plants. Bioactive molecules isolated …
Identification of antifungal targets based on computer modeling
Aspergillus fumigatus is a saprophytic, cosmopolitan fungus that attacks patients with a
weak immune system. A rational solution against fungal infection aims to manipulate fungal …
weak immune system. A rational solution against fungal infection aims to manipulate fungal …
GuiltyTargets: prioritization of novel therapeutic targets with network representation learning
The majority of clinical trials fail due to low efficacy of investigated drugs, often resulting from
a poor choice of target protein. Existing computational approaches aim to support target …
a poor choice of target protein. Existing computational approaches aim to support target …
[PDF][PDF] Pathogen and host-pathogen protein interactions provide a key to identify novel drug targets
Bacterial pathogens are a major cause of life-threatening diseases around the globe despite
all technological advances. Infections caused by bacterial pathogens are the most common …
all technological advances. Infections caused by bacterial pathogens are the most common …
Genome-wide inference of the Camponotus floridanus protein-protein interaction network using homologous mapping and interacting domain profile pairs
Apart from some model organisms, the interactome of most organisms is largely unidentified.
High-throughput experimental techniques to determine protein-protein interactions (PPIs) …
High-throughput experimental techniques to determine protein-protein interactions (PPIs) …
Pan-genomic analysis of the species Salmonella enterica: identification of core essential and putative essential genes
Background Essential genes are defined as the minimal gene set required to support
bacterial life. In order to develop new antimicrobials to treat multidrug-resistant pathogens …
bacterial life. In order to develop new antimicrobials to treat multidrug-resistant pathogens …