Methicillin-resistant Staphylococcus aureus: an overview of basic and clinical research

NA Turner, BK Sharma-Kuinkel… - Nature Reviews …, 2019 - nature.com
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most successful modern
pathogens. The same organism that lives as a commensal and is transmitted in both health …

Methicillin-resistant Staphylococcus aureus

AS Lee, H De Lencastre, J Garau… - Nature reviews Disease …, 2018 - nature.com
Since the 1960s, methicillin-resistant Staphylococcus aureus (MRSA) has emerged,
disseminated globally and become a leading cause of bacterial infections in both health …

Incidence, prevalence, and management of MRSA bacteremia across patient populations—a review of recent developments in MRSA management and treatment

A Hassoun, PK Linden, B Friedman - Critical care, 2017 - Springer
Methicillin-resistant Staphylococcus aureus (MRSA) infection is still a major global
healthcare problem. Of concern is S. aureus bacteremia, which exhibits high rates of …

Management considerations in infective endocarditis: a review

A Wang, JG Gaca, VH Chu - Jama, 2018 - jamanetwork.com
Importance Infective endocarditis occurs in approximately 15 of 100 000 people in the
United States and has increased in incidence. Clinicians must make treatment decisions …

Effect of vancomycin or daptomycin with vs without an antistaphylococcal β-lactam on mortality, bacteremia, relapse, or treatment failure in patients with MRSA …

SYC Tong, DC Lye, D Yahav, A Sud, JO Robinson… - Jama, 2020 - jamanetwork.com
Importance Methicillin-resistantStaphylococcus aureus (MRSA) bacteremia is associated
with mortality of more than 20%. Combining standard therapy with a β-lactam antibiotic has …

Antibiotic combination therapy against resistant bacterial infections: synergy, rejuvenation and resistance reduction

ARM Coates, Y Hu, J Holt, P Yeh - Expert review of Anti-infective …, 2020 - Taylor & Francis
ABSTRACT Introduction: Anti-Microbial Resistance (AMR) is a pandemic which threatens
modern medicine. There is a lack of effective drug treatment due to the slow pace, high cost …

[PDF][PDF] Treatment of methicillin-resistant Staphylococcus aureus (MRSA): updated guidelines from the UK

NM Brown, AL Goodman, C Horner… - JAC-antimicrobial …, 2021 - academic.oup.com
These evidence-based guidelines are an updated version of those issued in 2008. They
have been produced following a review of the published literature (2007–18) pertaining to …

Clinical data on daptomycin plus ceftaroline versus standard of care monotherapy in the treatment of methicillin-resistant Staphylococcus aureus bacteremia

M Geriak, F Haddad, K Rizvi, W Rose… - Antimicrobial agents …, 2019 - Am Soc Microbiol
Vancomycin (VAN) and daptomycin (DAP) are approved as a monotherapy for methicillin-
resistant Staphylococcus aureus (MRSA) bacteremia. A regimen of daptomycin plus …

β-Lactams against the Fortress of the Gram-Positive Staphylococcus aureus Bacterium

JF Fisher, S Mobashery - Chemical reviews, 2020 - ACS Publications
The biological diversity of the unicellular bacteria—whether assessed by shape, food,
metabolism, or ecological niche—surely rivals (if not exceeds) that of the multicellular …

Daptomycin Plus Fosfomycin Versus Daptomycin Alone for Methicillin-resistant Staphylococcus aureus Bacteremia and Endocarditis: A Randomized Clinical Trial

M Pujol, JM Miró, E Shaw, JM Aguado… - Clinical Infectious …, 2021 - academic.oup.com
Background We aimed to determine whether daptomycin plus fosfomycin provides higher
treatment success than daptomycin alone for methicillin-resistant Staphylococcus aureus …