The Rickettsiales are a group of obligate intracellular vector-borne Gram-negative bacteria
that include many organisms of clinical and agricultural importance, including Anaplasma …

Human ehrlichiosis and anaplasmosis are acute febrile tick-borne diseases caused by
various members from the genera Ehrlichia and Anaplasma. 1–5 Ehrlichia chaffeensis is the …

Activating inflammatory caspases and releasing pro-inflammatory mediators are two
essential functions of inflammasomes which are triggered in response to pathogen …

Ehrlichia is Gram negative obligate intracellular bacterium that cause human monocytotropic
ehrlichiosis (HME). HME is characterized by acute liver damage and inflammation that may …

The host-pathogen interface is a crucial battleground during bacterial infection in which host
defenses are met with an array of bacterial counter-mechanisms whereby the invader aims …

Sulfate Reducing Bacteria (SRB), usually rare residents of the gut, are often found in
increased numbers (called a SRB bloom) in inflammatory conditions such as Inflammatory …

Intracellular bacteria have evolved various strategies to evade host defense mechanisms.
Remarkably, the obligately intracellular bacterium, Ehrlichia chaffeensis, hijacks host cell …

Ehrlichia chaffeensis TRP120 effector has evolved short linear motif (SLiM) ligand mimicry to
repurpose multiple evolutionarily conserved cellular signaling pathways, including Wnt …

Notch signalling is an evolutionarily highly conserved pathway that plays a crucial role
during embryonic development and in tissue homeostasis maintenance during adult life …

Ehrlichia chaffeensis has evolved multiple strategies to evade innate defenses of the
mononuclear phagocyte. Recently, we reported the E. chaffeensis tandem repeat protein …