Moderation of hyperuricemia in rats via consuming walnut protein hydrolysate diet and identification of new antihyperuricemic peptides

Q Li, X Kang, C Shi, Y Li, K Majumder, Z Ning, J Ren - Food & Function, 2018 - pubs.rsc.org
In this study, walnut meal hydrolysates (WMH) and dephenolized walnut meal hydrolysates
(DWMH) were found to effectively decrease the serum uric acid level and protect the renal …

Anti-hyperuricemic peptides derived from bonito hydrolysates based on in vivo hyperuricemic model and in vitro xanthine oxidase inhibitory activity

Y Li, X Kang, Q Li, C Shi, Y Lian, E Yuan, M Zhou… - Peptides, 2018 - Elsevier
Traditional drugs used to treat hyperuricemia have adverse effects. In this study, to identify
safer anti-hyperuricemic bioactive peptides isolated from food-derived protein hydrolysates …

Multiple system organ response induced by hyperoxia in a clinically relevant animal model of sepsis

R Rodríguez-González, JL Martín-Barrasa… - Shock, 2014 - journals.lww.com
Oxygen therapy is currently used as a supportive treatment in septic patients to improve
tissue oxygenation. However, oxygen can exert deleterious effects on the inflammatory …

[HTML][HTML] Resveratrol protects against early polymicrobial sepsis-induced acute kidney injury through inhibiting endoplasmic reticulum stress-activated NF-κB pathway

N Wang, L Mao, L Yang, J Zou, K Liu, M Liu, H Zhang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Resveratrol, a polyphenol compound derived from various edible plants, protects against
sepsis-induced acute kidney injury (AKI) via its anti-inflammatory activity, but the underlying …

Xanthine oxidase inhibitory activity and antihyperuricemic effect of Moringa oleifera Lam. leaf hydrolysate rich in phenolics and peptides

Y Tian, L Lin, M Zhao, A Peng, K Zhao - Journal of Ethnopharmacology, 2021 - Elsevier
Abstract Ethnopharmacological relevance Moringa oleifera Lam. leaf (MOL), a rich source of
protein and phenolics, was traditionally used to treat various diseases including headaches …

The significance of routine biochemical markers in patients with major depressive disorder

YF Peng, Y Xiang, YS Wei - Scientific reports, 2016 - nature.com
The aim of our study is to examine the levels of routine biochemical markers in patients with
major depressive disorder (MDD), and combine multiple biochemical parameters to assess …

Protein kinase G oxidation is a major cause of injury during sepsis

O Rudyk, A Phinikaridou… - Proceedings of the …, 2013 - National Acad Sciences
Sepsis is a common life-threatening clinical syndrome involving complications as a result of
severe infection. A cardinal feature of sepsis is inflammation that results in oxidative stress …

[HTML][HTML] Sinomenine hydrochloride protects against polymicrobial sepsis via autophagy

Y Jiang, M Gao, W Wang, Y Lang, Z Tong… - International Journal of …, 2015 - mdpi.com
Sepsis, a systemic inflammatory response to infection, is the major cause of death in
intensive care units (ICUs). The mortality rate of sepsis remains high even though the …

Effect of celecoxib and infliximab against multiple organ damage induced by sepsis in rats: A comparative study

SR Senousy, M El-Daly, ARN Ibrahim, MMA Khalifa… - Biomedicines, 2022 - mdpi.com
In cases of sepsis, the immune system responds with an uncontrolled release of
proinflammatory cytokines and reactive oxygen species. The lungs, kidneys, and liver are …

Clinical associations of host genetic variations in the genes of cytokines in critically ill patients

OB Belopolskaya, TV Smelaya… - Clinical & …, 2015 - academic.oup.com
Host genetic variations may influence a changing profile of biochemical markers and
outcome in patients with trauma/injury. The objective of this study was to assess clinical …