Epigenetic Manipulation of Psychiatric Behavioral Disorders Induced by Toxoplasma gondii

K Yin, C Xu, G Zhao, H Xie - Frontiers in cellular and infection …, 2022 - frontiersin.org
Toxoplasma gondii is known to have a complex life cycle and infect almost all kinds of warm-
blooded animals around the world. The brain of the host could be persistently infected by …

A pre-existing Toxoplasma gondii infection exacerbates the pathophysiological response and extent of brain damage after traumatic brain injury in mice

TL Baker, DK Wright, AD Uboldi, CJ Tonkin… - Journal of …, 2024 - Springer
Traumatic brain injury (TBI) is a key contributor to global morbidity that lacks effective
treatments. Microbial infections are common in TBI patients, and their presence could modify …

Behavioral alterations in long-term Toxoplasma gondii infection of C57BL/6 mice are associated with neuroinflammation and disruption of the blood brain barrier

L Castaño Barrios, AP Da Silva Pinheiro, D Gibaldi… - Plos one, 2021 - journals.plos.org
The Apicomplexa protozoan Toxoplasma gondii is a mandatory intracellular parasite and
the causative agent of toxoplasmosis. This illness is of medical importance due to its high …

A metabolite attenuates neuroinflammation, synaptic loss and cognitive deficits induced by chronic infection of Toxoplasma gondii

Y He, D Xu, Z Yan, Y Wu, Y Zhang, X Tian… - Frontiers in …, 2022 - frontiersin.org
Background Neurodegenerative diseases including AD is currently one of intractable
problems globally due to the insufficiency of intervention strategies. Long-term infection of …

Ginger is a potential therapeutic for chronic toxoplasmosis

AM El-Kady, WAI Al-Megrin, IAM Abdel-Rahman… - Pathogens, 2022 - mdpi.com
Background: Toxoplasma gondii (T. gondii) is an opportunistic parasite that causes serious
diseases in humans, particularly immunocompromised individuals and pregnant women. To …

Research Progress on the Association between Schizophrenia and Toxoplasma gondii Infection

Y Zhu, X Yang, M Chen, Y Hu, Y Chang… - Biomedical and …, 2024 - Elsevier
Toxoplasma gondii (T. gondii or Tg), is an obligatory intracellular parasite with humans as its
intermediate hosts. In recent years, significant correlations between T. gondii infection and …

Anti-toxoplasmic effects of celecoxib alone and combined with spiramycin in experimental mice

SS Shendi, SM Selim, SA Sharaf, MA Gouda… - Acta Tropica, 2024 - Elsevier
Even though toxoplasmosis is a worldwide parasitic disease caused by Toxoplasma gondii
(T. gondii), the available drugs used for the treatment of symptomatic toxoplasmosis have …

Protection Induced by Vaccination with Recombinant Baculovirus and Virus-like Particles Expressing Toxoplasma gondii Rhoptry Protein 18

KW Yoon, KB Chu, HJ Kang, MJ Kim, GD Eom, J Mao… - Vaccines, 2022 - mdpi.com
Heterologous immunization is garnering attention as a promising strategy to improve
vaccine efficacy. Vaccines based on recombinant baculovirus (rBV) and virus-like particle …

Kinematic changes in a mouse model of penetrating hippocampal injury and their recovery after intranasal administration of endometrial mesenchymal stem cell …

LC León-Moreno, R Castañeda-Arellano… - Frontiers in Cellular …, 2020 - frontiersin.org
Locomotion speed changes appear following hippocampal injury. We used a hippocampal
penetrating brain injury mouse model to analyze other kinematic changes. We found a …

[PDF][PDF] ReseaRch aRticle The superior efficacy of chloroquine over buparvaquone in reducing the chronic cerebral Toxoplasma gondiicysts load and improving the …

MEA Fahmy, AA Abdel-Aal, SI Hassan… - Tropical …, 2023 - msptm.org
Toxoplasma gondii, the etiologic agent of toxoplasmosis, infects about 30–50% of the world
population. The currently available anti-Toxoplasma agents have serious limitations. The …