Bat-borne virus diversity, spillover and emergence

M Letko, SN Seifert, KJ Olival, RK Plowright… - Nature Reviews …, 2020 - nature.com
Most viral pathogens in humans have animal origins and arose through cross-species
transmission. Over the past 50 years, several viruses, including Ebola virus, Marburg virus …

Henipavirus zoonosis: outbreaks, animal hosts and potential new emergence

H Li, JYV Kim, BS Pickering - Frontiers in microbiology, 2023 - frontiersin.org
Hendra virus (HeV) and Nipah virus (NiV) are biosafety level 4 zoonotic pathogens causing
severe and often fatal neurological and respiratory disease. These agents have been …

Broadly neutralizing antibody cocktails targeting Nipah virus and Hendra virus fusion glycoproteins

HV Dang, RW Cross, V Borisevich… - Nature Structural & …, 2021 - nature.com
Abstract Hendra virus (HeV) and Nipah virus (NiV) are henipaviruses (HNVs) causing
respiratory illness and severe encephalitis in humans, with fatality rates of 50–100%. There …

Receptor-mediated cell entry of paramyxoviruses: Mechanisms, and consequences for tropism and pathogenesis

CK Navaratnarajah, AR Generous, I Yousaf… - Journal of Biological …, 2020 - ASBMB
Research in the last decade has uncovered many new paramyxoviruses, airborne agents
that cause epidemic diseases in animals including humans. Most paramyxoviruses enter …

Potent monoclonal antibody–mediated neutralization of a divergent Hendra virus variant

Z Wang, HV Dang, M Amaya, Y Xu… - Proceedings of the …, 2022 - National Acad Sciences
Hendra virus (HeV) and Nipah virus (NiV) are deadly zoonotic Henipaviruses (HNVs)
responsible for recurrent outbreaks in humans and domestic species of highly fatal (50 to …

Differential innate immune responses elicited by Nipah virus and Cedar virus correlate with disparate in vivo pathogenesis in hamsters

T Schountz, C Campbell, K Wagner, J Rovnak… - Viruses, 2019 - mdpi.com
Syrian hamsters (Mesocricetus auratus) are a pathogenesis model for the Nipah virus (NiV),
and we sought to determine if they are also susceptible to the Cedar virus (CedPV) …

Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus

ED Laing, CK Navaratnarajah… - Proceedings of the …, 2019 - National Acad Sciences
Cedar virus (CedV) is a bat-borne henipavirus related to Nipah virus (NiV) and Hendra virus
(HeV), zoonotic agents of fatal human disease. CedV receptor-binding protein (G) shares …

Enhanced autophagy contributes to reduced viral infection in black flying fox cells

ED Laing, SL Sterling, DL Weir, CR Beauregard… - Viruses, 2019 - mdpi.com
Bats are increasingly implicated as hosts of highly pathogenic viruses. The underlying virus–
host interactions and cellular mechanisms that promote co-existence remain ill-defined, but …

[HTML][HTML] Ephrin-Eph signaling usage by a variety of viruses

ECW de Boer, JM van Gils, MJ van Gils - Pharmacological Research, 2020 - Elsevier
Ephrin-Eph signaling is a receptor tyrosine kinase signaling pathway involved in a variety of
cellular mechanisms, of which many are related to the adhesion or migration of cells. Both …

Henipavirus-induced neuropathogenesis in mice

SJ Edwards, B Rowe, T Reid, M Tachedjian, S Caruso… - Virology, 2023 - Elsevier
Abstract Hendra virus (HeV) and Nipah virus (NiV) are henipaviruses that can cause fatal
encephalitis in humans. Many animal models have been used to study henipavirus …