Abstract mRNA vaccines have emerged as a revolutionary tool to generate rapid and
precise immune responses against infectious diseases and cancers. Compared with …

Lipid nanoparticles (LNPs) have emerged across the pharmaceutical industry as promising
vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital components of …

A Comprehensive Review of the Global Efforts on COVID-19 Vaccine Development | ACS
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In 2021, mRNA vaccines against COVID-19 were approved by the Food and Drug
Administration. mRNA vaccines are important for preventing severe COVID-19 and returning …

Vaccination represents the best line of defense against infectious diseases and is crucial in
curtailing pandemic spread of emerging pathogens to which a population has limited …

The remarkable impact of mRNA vaccines on mitigating disease and improving public
health has been amply demonstrated during the COVID-19 pandemic. Many new mRNA …

Despite exciting advances in gene editing, the efficient delivery of genetic tools to
extrahepatic tissues remains challenging. This holds particularly true for the skin, which …

Introduction Vaccination is so far the most effective way of eradicating infections. Rapidly
emerging drug resistance against infectious diseases and chemotherapy-related toxicities in …

Efficient cytosolic delivery of RNA molecules remains a formidable barrier for RNA
therapeutic strategies. Lipid nanoparticles (LNPs) serve as state-of-the-art carriers that can …

Gene editing mediated by CRISPR/Cas9 systems is due to become a beneficial therapeutic
option for treating genetic diseases and some cancers. However, there are challenges in …