Paracoccidioidomycosis is a systemic mycosis endemic to Latin America, with
Paracoccidioides brasiliensis and P. lutzii being the causal agents of this disorder. Several …

Paracoccidioides brasiliensis is a temperature-dependent dimorphic fungus and the agent
of paracoccidioidomycosis (PCM), which is prevalent in rural workers of Latin American …

Paracoccidioides brasiliensis is characterized by a multiple budding phenotype and a
polymorphic cell growth, leading to the formation of cells with extreme variations in shape …

We herein report the development of a molecular toolbox for the dimorphic fungus
Paracoccidioides brasiliensis, specifically a more efficient transformation and a gene …

In the yeast Saccharomyces cerevisiae, interventions resembling caloric restriction, either by
reduction of glucose or non-essential amino acid content in the medium, prolong life span …

The aim of this study was to evaluate genome size and ploidy of the dimorphic pathogenic
fungus Paracoccidioides brasiliensis. The cell cycle analysis of 10 P. brasiliensis isolates by …

Ploidy is a fundamental genetic trait with important physiological and genomic implications.
We applied complementary molecular tools to highlight differences in genome size and …

Background The Fungal Genome Initiative of the Broad Institute, in partnership with the
Paracoccidioides research community, has recently sequenced the genome of …

Genome size has played an important role in the evolution of plants and animals because
changes in genome size seem to accompany if not facilitate evolutionary adaptation to …

Recent evidence suggests that Paracoccidioides species have the potential to undergo
sexual reproduction, although no sexual cycle has been identified either in nature or under …