Ischaemic stroke is a leading cause of disability and death for which no acute treatments
exist beyond recanalization. The development of novel therapies has been repeatedly …

Autophagy is a strictly regulated process that degrades and recycles long-lived or misfolded
proteins and damaged organelles for the maintenance of energy and function homeostasis …

Microglial phagocytosis of apoptotic debris prevents buildup damage of neighbor neurons
and inflammatory responses. Whereas microglia are very competent phagocytes under …

Stroke is the second leading cause of death globally and the most common cause of severe
disability. Several barriers need to be addressed more effectively to treat stroke, including …

Stroke is one of the leading causes of death and disability worldwide. Autophagy is a
conserved cellular catabolic pathway that maintains cellular homeostasis by removal of …

Animals live in habitats fraught with a range of environmental challenges to their bodies and
brains. Accordingly, cells and organ systems have evolved stress-responsive signaling …

Understanding cell-specific transcriptome responses following intracerebral hemorrhage
(ICH) and ischemic stroke (IS) will improve knowledge of the immune response to brain …

Perinatal hypoxic ischemic encephalopathy (HIE) results in serious neurological dysfunction
and mortality. Clinical trials of multilineage-differentiating stress enduring cells (Muse cells) …

Stroke is among the leading causes of death and disability worldwide. Restoring blood flow
through recanalization is currently the only acute treatment for cerebral ischemia …

Abstract Background Sturge-Weber syndrome is a rare neurovascular disorder associated
with capillary malformation, seizures, cognitive impairments, and stroke-like episodes …