Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. As a
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …

Brucellosis is a worldwide zoonosis affecting animal and human health. In the last several
decades, much research has been performed to develop safer Brucella vaccines to control …

There is currently no licensed vaccine for brucellosis in humans. Available animal vaccines
may cause disease and are considered unsuitable for use in humans. However, the …

Brucellosis is a worldwide zoonosis affecting animal and human health. Till now, there is no
effective vaccine licensed for brucellosis in humans. Although M5, H38 and 45/20 vaccines …

Brucella spp. are zoonotic, facultative intracellular pathogens, which cause animal and
human disease. Animal disease results in abortion of fetuses; in humans, it manifests flu-like …

Prophylactic vaccines have evolved from traditional whole-cell vaccines to safer subunit
vaccines. However, subunit vaccines still face problems, such as poor immunogenicity and …

Alphavirus vectors are high-level, transient expression vectors for therapeutic and
prophylactic use. These positive-stranded RNA vectors, derived from Semliki Forest virus …

Brucella infections mainly occur through mucosal surfaces. Thus, the development of
mucosal administered vaccines could be instrumental for the control of brucellosis. Here, we …

Background/Objectives In spite of all the research effort for developing new vaccines against
brucellosis, it remains unclear whether these new vaccine technologies will in fact become …

Brucella abortus is a Gram-negative facultative and intracellular bacteria, it causes bovine
brucellosis, a zoonotic disease that is responsible for considerable economic loss to owners …