Aging is associated with an increased incidence of cardiovascular disease and thrombosis.
Platelets play a major role in maintaining hemostasis and in thrombus formation, making …

Since December 2019 the novel coronavirus SARS-CoV-2 has been identified as the cause
of the pandemic COVID-19. Early symptoms overlap with other common conditions such as …

Background Although immune modulation is a promising therapeutic avenue in coronavirus
disease 2019 (COVID-19), the most relevant targets remain to be found. COVID-19 has …

There are clear age-related changes in platelet count and function, driven by changes in
hematopoietic tissue, the composition of the blood and vascular health. Platelet count …

Despite the ongoing development of automated hematology analyzers to optimize complete
blood count results, platelet count still suffers from pre-analytical or analytical pitfalls …

The term “benign ethnic neutropenia” describes the phenotype of having an absolute
neutrophil count (ANC)< 1500 cells/μL with no increased risk of infection. It is most …

Although there have been advances dissecting the molecular mechanisms regarding aging-
related changes in platelets, many knowledge gaps still remain. Studies filling these gaps …

Background Female sex confers a survival advantage following severe injury in the setting
of trauma‐induced coagulopathy, with female platelets having heightened responsiveness …

Background Platelets are part of innate immunity and comprise the cellular portion of
hemostasis. Platelets express sex hormone receptors on their plasma membrane and sex …

Background Biological age (BA) has been recognized as a more accurate indicator of aging
than chronological age (CA). However, the current limitations include: insufficient attention to …