JA Holbrook, HH Jarosz-Griffiths, E Caseley… - Frontiers in …, 2021 - frontiersin.org
The prevalence of neurodegenerative disease has increased significantly in recent years, and with a rapidly aging global population, this trend is expected to continue. These …
C Zhao, H Deng, X Chen - Advanced Drug Delivery Reviews, 2022 - Elsevier
With the increasing understanding of various biological functions mediated by reactive oxygen species (ROS) in the immune system, a number of studies have been designed to …
ŞE Erdener, Z Kaya, T Dalkara - The journal of headache and pain, 2021 - Springer
Background Pain is generally concomitant with an inflammatory reaction at the site where the nociceptive fibers are activated. Rodent studies suggest that a sterile meningeal …
S Roy, MA Ansari, K Choudhary, S Singh - International …, 2023 - Elsevier
The present article provides a detailed concept of the role of NLRP3 inflammasome in the pathophysiology of depression-like chronic diseases where inflammation and release of …
H Malcova, Z Strizova, T Milota, I Striz… - Frontiers in …, 2021 - frontiersin.org
Autoinflammatory diseases (AIDs) represent a rare and heterogeneous group of disorders characterized by recurrent episodes of inflammation and a broad range of clinical …
Inflammasomes are assembled by innate immune sensors that cells employ to detect a range of danger signals and respond with pro‐inflammatory signalling. Inflammasomes …
SR Bonam, D Mastrippolito, P Georgel… - Trends in Pharmacological …, 2024 - cell.com
Many aspects of cell homeostasis and integrity are maintained by the nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family pyrin domain-containing 3 …
Cerebral ischemia reperfusion injury is a debilitating medical condition, currently with only a limited amount of therapies aimed at protecting the cerebral parenchyma. Micro RNAs …
Inflammatory bowel disease (IBD) remains a persistent health problem with a global burden surging over 6.8 million cases currently. Clinical pathology of IBD is complicated; however …