Manganese-enhanced magnetic resonance imaging: overview and central nervous system applications with a focus on neurodegeneration

RA Cloyd, SA Koren, JF Abisambra - Frontiers in aging neuroscience, 2018 - frontiersin.org
Manganese-enhanced magnetic resonance imaging (MEMRI) rose to prominence in the
1990s as a sensitive approach to high contrast imaging. Following the discovery of …

Early or late gestational exposure to maternal immune activation alters neurodevelopmental trajectories in mice: an integrated neuroimaging, behavioral, and …

E Guma, P do Couto Bordignon, GA Devenyi… - Biological …, 2021 - Elsevier
Background Exposure to maternal immune activation (MIA) in utero is a risk factor for
neurodevelopmental disorders later in life. The impact of the gestational timing of MIA …

Longitudinal manganese‐enhanced magnetic resonance imaging of neural projections and activity

TW Uselman, CS Medina, HB Gray… - NMR in …, 2022 - Wiley Online Library
Manganese‐enhanced magnetic resonance imaging (MEMRI) holds exceptional promise
for preclinical studies of brain‐wide physiology in awake‐behaving animals. The objectives …

[HTML][HTML] Contributions of a high-fat diet to Alzheimer's disease-related decline: a longitudinal behavioural and structural neuroimaging study in mouse models

CPE Rollins, D Gallino, V Kong, G Ayranci… - NeuroImage: Clinical, 2019 - Elsevier
Obesity is recognized as a significant risk factor for Alzheimer's disease (AD). Studies have
supported that obesity accelerates AD-related pathophysiology and memory impairment in …

[HTML][HTML] Examining litter specific variability in mice and its impact on neurodevelopmental studies

V Valiquette, E Guma, L Cupo, D Gallino… - Neuroimage, 2023 - Elsevier
Our current understanding of litter variability in neurodevelopmental studies using mice may
limit translation of neuroscientific findings. Higher variance of measures across litters than …

Longitudinal assessment of the neuroanatomical consequences of deep brain stimulation: Application of fornical DBS in an Alzheimer's mouse model

D Gallino, GA Devenyi, J Germann, E Guma… - Brain research, 2019 - Elsevier
Following its success in the treatment of refractory movement disorders, deep brain
stimulation (DBS) is currently under clinical investigation as a possible treatment for several …

Applications of manganese-enhanced magnetic resonance imaging in ophthalmology and visual neuroscience

W Deng, MA Faiq, C Liu, V Adi, KC Chan - Frontiers in Neural Circuits, 2019 - frontiersin.org
Understanding the mechanisms of vision in health and disease requires knowledge of the
anatomy and physiology of the eye and the neural pathways relevant to visual perception …

[HTML][HTML] Evolution of brain-wide activity in the awake behaving mouse after acute fear by longitudinal manganese-enhanced MRI

TW Uselman, DR Barto, RE Jacobs, EL Bearer - Neuroimage, 2020 - Elsevier
Life threatening fear after a single exposure evolves in a subset of vulnerable individuals to
anxiety, which may persist for their lifetime. Yet neither the whole brain's response to innate …

Preventive impacts of PAS-Na on the slow growth and activated inflammatory responses in Mn-exposed rats

DJ Peng, YW Zhang, Z Li, SJ Li, M Cai, WX Qin… - Journal of Trace …, 2019 - Elsevier
Background Sodium para-aminosalicylic acid (PAS-Na), an anti-tuberculosis drug, has been
demonstrated its function in facilitating the Mn elimination in manganism patients and Mn …

[HTML][HTML] Examining the effect of chronic intranasal oxytocin administration on the neuroanatomy and behavior of three autism-related mouse models

Z Lindenmaier, J Ellegood, M Stuive, K Easson, Y Yee… - NeuroImage, 2022 - Elsevier
Although initially showing great potential, oxytocin treatment has encountered a translational
hurdle in its promise of treating the social deficits of autism. Some debate surrounds the …