The SLC4 family consists of 10 genes (SLC4A1–5; SLC4A7–11). All encode integral
membrane proteins with very similar hydropathy plots—consistent with 10–14 …

The crystal structure of the dimeric membrane domain of human Band 3 1, the red cell
chloride/bicarbonate anion exchanger 1 (AE1, SLC4A1), provides a structural context for …

The stability and shape of the erythrocyte membrane is provided by the ankyrin-1 complex,
but how it tethers the spectrin–actin cytoskeleton to the lipid bilayer and the nature of its …

The mammalian Slc4 (Solute carrier 4) family of transporters is a functionally diverse group
of 10 multi-spanning membrane proteins that includes three Cl-HCO3 exchangers (AE1–3) …

The major transmembrane protein of the red blood cell, known as band 3, AE1, and
SLC4A1, has two main functions: 1) catalysis of Cl−/HC O 3− exchange, one of the steps in …

SUMMARY Plasmalemmal Cl–/HCO3–exchangers are encoded by the SLC4 and SLC26
gene superfamilies, and function to regulate intracellular pH,[Cl–] and cell volume. The Cl …

The primary or hereditary forms of distal renal tubular acidosis (dRTA) have received
increased attention because of advances in the understanding of the molecular mechanism …

An overview about erythrocyte membrane Page 1 Clinical Hemorheology and
Microcirculation 44 (2010) 63–74 63 DOI 10.3233/CH-2010-1253 IOS Press An overview …

Plasmodium falciparum invasion of human red blood cells (RBCs) is an intricate process
requiring a number of distinct ligand-receptor interactions at the merozoite-erythrocyte …

The cells in animals face unique demands beyond those encountered by their unicellular
eukaryotic ancestors. For example, the forces engendered by the movement of animals …