Plant-associated endophytes define an important symbiotic association in nature and are
established bio-reservoirs of plant-derived natural products. Endophytes colonize the …

Cancer is a major cause of death worldwide, with an increasing number of cases being
reported annually. The elevated rate of mortality necessitates a global challenge to explore …

Coronavirus disease strain (SARS-CoV-2) was discovered in 2019, and it is spreading very
fast around the world causing the disease Covid-19. Currently, more than 1.6 million …

Throughout history, natural products have afforded a rich source of compounds that have
found many applications in the fields of medicine, pharmacy and biology. Within the sphere …

The lignan family of natural products includes compounds with important antineoplastic and
antiviral properties such as podophyllotoxin and two of their semisynthetic derivatives …

The chemical structures and antiviral activities of 52 lignans are reviewed. It is seen that
while the antiviral effects of lignans are not strong, several modes of antiviral activity are …

Podophyllotoxin (PPT), as well as its congeners and derivatives, exhibits pronounced
biological activities, especially antineoplastic effects. Its strong inhibitory effect on tumor cell …

This report is presented in essentially the same style and format as the previous two reports
in the series.', 2 In addition the abbreviations used for different aryl groups are continued …

Tubulin being a major cellular target for antitumor drugs, tubulin-interacting compounds
have attracted great attention as antimitotic agents. Two main classes of antimitotic drugs …

The study reported herein utilized the Agrobacterium tumefaciens-induced potato disc tumor
assay. The objective was to verify the detection of antineoplastic activity in the potato disc …