Cytokinins: Wide-spread signaling hormones from plants to humans with high medical potential

M Fathy, SM Saad Eldin, M Naseem, T Dandekar… - Nutrients, 2022 - mdpi.com
Nature is a rich source of biologically active novel compounds. Sixty years ago, the plant
hormones cytokinins were first discovered. These play a major role in cell division and cell …

Beyond transport: cytokinin ribosides are translocated and active in regulating the development and environmental responses of plants

HN Nguyen, TQ Nguyen, AB Kisiala, RJN Emery - Planta, 2021 - Springer
Main conclusion Riboside type cytokinins are key components in cytokinin metabolism,
transport, and sensitivity, making them important functional signals in plant growth and …

Trichoderma Synthesizes Cytokinins and Alters Cytokinin Dynamics of Inoculated Arabidopsis Seedlings

KM Bean, AB Kisiala, EN Morrison… - Journal of Plant Growth …, 2022 - Springer
Trichoderma is an important genus of symbiotic fungi, commonly used around the world as
biocontrol agents and as biofertilizer. Although their beneficial effects are well known and …

The origins and roles of methylthiolated cytokinins: Evidence from among life kingdoms

M Gibb, AB Kisiala, EN Morrison… - Frontiers in Cell and …, 2020 - frontiersin.org
Cytokinins (CKs) are a group of adenine-derived, small signaling molecules of crucial
importance for growth and multiple developmental processes in plants. Biological roles of …

Cytokinins are abundant and widespread among insect species

P Andreas, A Kisiala, RJN Emery, R De Clerck-Floate… - Plants, 2020 - mdpi.com
Cytokinins (CKs) are a class of compounds that have long been thought to be exclusively
plant growth regulators. Interestingly, some species of phytopathogenic bacteria and fungi …

Modulatory and toxicological perspectives on the effects of the small molecule kinetin

EM Othman, M Fathy, AA Bekhit, ARH Abdel-Razik… - Molecules, 2021 - mdpi.com
Plant hormones are small regulatory molecules that exert pharmacological actions in
mammalian cells such as anti-oxidative and pro-metabolic effects. Kinetin belongs to the …

Phytohormone profiling in an evolutionary framework

V Schmidt, R Skokan, T Depaepe, K Kurtović… - Nature …, 2024 - nature.com
The genomes of charophyte green algae, close relatives of land plants, typically do not show
signs of developmental regulation by phytohormones. However, scattered reports of …

Soil health improvements under cover crops are associated with enhanced soil content of cytokinins

I Perera, A Kisiala, KA Thompson, RJN Emery - Plant Biology, 2024 - Wiley Online Library
Cytokinins (CKs) are phytohormones produced by plants and other soil life. including
bacteria, fungi, insects, and earthworms. These organisms can release CKs to the soil …

Integrated structural and functional analysis of the protective effects of kinetin against oxidative stress in mammalian cellular systems

M Naseem, EM Othman, M Fathy, J Iqbal, FM Howari… - Scientific reports, 2020 - nature.com
Metabolism and signaling of cytokinins was first established in plants, followed by cytokinin
discoveries in all kingdoms of life. However, understanding of their role in mammalian cells …

Cultivation of heterotrophic Euglena gracilis: The effects of recycled media on culture growth and associations with growth regulating phytohormone profiles

AM Kuhne, EN Morrison, T Sultana, AB Kisiala… - Journal of Applied …, 2023 - Springer
In response to the rapid expansion of the worldwide population, there is an urgent need for
the development of new, more environmentally-conscious, food sources. In this context …