Machine learning strategies in microRNA research: bridging genome to phenome

S Daniel Thomas, K Vijayakumar, L John… - OMICS: A Journal of …, 2024 - liebertpub.com
MicroRNAs (miRNAs) have emerged as a prominent layer of regulation of gene expression.
This article offers the salient and current aspects of machine learning (ML) tools and …

Small RNA targets: advances in prediction tools and high-throughput profiling

K Grešová, P Alexiou, IC Giassa - Biology, 2022 - mdpi.com
Simple Summary MicroRNAs (miRNAs) are a category of small RNAs (sRNAs) that have
been found to regulate gene expression. Through the mediation of proteins from the …

What variables are important in predicting bovine viral diarrhea virus? A random forest approach

G Machado, MR Mendoza, LG Corbellini - Veterinary research, 2015 - Springer
Bovine viral diarrhea virus (BVDV) causes one of the most economically important diseases
in cattle, and the virus is found worldwide. A better understanding of the disease associated …

P-TarPmiR accurately predicts plant-specific miRNA targets

V Ajila, L Colley, DT Ste-Croix, N Nissan, A Golshani… - Scientific Reports, 2023 - nature.com
Abstract microRNAs (miRNAs) are small non-coding ribonucleic acids that post-
transcriptionally regulate gene expression through the targeting of messenger RNA …

Diagnostic model generated by MRI‐derived brain features in toddlers with autism spectrum disorder

X Xiao, H Fang, J Wu, CY Xiao, T Xiao, L Qian… - Autism …, 2017 - Wiley Online Library
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder mainly showed
atypical social interaction, communication, and restricted, repetitive patterns of behavior …

Species-specific microRNA discovery and target prediction in the soybean cyst nematode

V Ajila, L Colley, DT Ste-Croix, N Nissan, ER Cober… - Scientific Reports, 2023 - nature.com
The soybean cyst nematode (SCN) is a devastating pathogen for economic and food
security considerations. Although the SCN genome has recently been sequenced, the …

[HTML][HTML] Identification of prognostic biomarkers in glioblastoma using a long non-coding RNA-mediated, competitive endogenous RNA network

Y Cao, P Wang, S Ning, W Xiao, B Xiao, X Li - Oncotarget, 2016 - ncbi.nlm.nih.gov
Glioblastoma multiforme (GBM) is a highly malignant brain tumor associated with a poor
prognosis. Cross-talk between competitive endogenous RNAs (ceRNAs) plays a critical role …

RPmirDIP: Reciprocal Perspective improves miRNA targeting prediction

DG Kyrollos, B Reid, K Dick, JR Green - Scientific reports, 2020 - nature.com
MicroRNAs (miRNAs) are short, non-coding RNAs that interact with messenger RNA
(mRNA) to accomplish critical cellular activities such as the regulation of gene expression …

Improving miRNA-mRNA interaction predictions

D Tabas-Madrid, A Muniategui, I Sánchez-Caballero… - BMC genomics, 2014 - Springer
Background MicroRNAs are short RNA molecules that post-transcriptionally regulate gene
expression. Today, microRNA target prediction remains challenging since very few have …

Comparative Analyses between Retained Introns and Constitutively Spliced Introns in Arabidopsis thaliana Using Random Forest and Support Vector Machine

R Mao, PK Raj Kumar, C Guo, Y Zhang, C Liang - PLoS One, 2014 - journals.plos.org
One of the important modes of pre-mRNA post-transcriptional modification is alternative
splicing. Alternative splicing allows creation of many distinct mature mRNA transcripts from a …