New and established technology in focal ablation of the prostate: a systematic review

M Valerio, Y Cerantola, SE Eggener, H Lepor… - European urology, 2017 - Elsevier
Context Focal therapy of prostate cancer has been proposed as an alternative to whole-
gland treatments. Objective To summarize the evidence regarding sources of energy …

Irreversible electroporation: background, theory, and review of recent developments in clinical oncology

KN Aycock, RV Davalos - Bioelectricity, 2019 - liebertpub.com
Irreversible electroporation (IRE) has established a clinical niche as an alternative to thermal
ablation for the eradication of unresectable tumors, particularly those near critical vascular …

High-frequency irreversible electroporation is an effective tumor ablation strategy that induces immunologic cell death and promotes systemic anti-tumor immunity

VM Ringel-Scaia, N Beitel-White, MF Lorenzo… - …, 2019 - thelancet.com
Background Despite promising treatments for breast cancer, mortality rates remain high and
treatments for metastatic disease are limited. High-frequency irreversible electroporation (H …

An update on focal therapy for prostate cancer

M Perera, N Krishnananthan, U Lindner… - Nature Reviews …, 2016 - nature.com
Globally, the increased uptake of serum PSA level screening led to an increase in the
number of diagnoses of low-risk and intermediate-risk prostate cancer. Traditionally, these …

Irreversible electroporation: state of the art

PGK Wagstaff, M Buijs, W van den Bos… - OncoTargets and …, 2016 - Taylor & Francis
The field of focal ablative therapy for the treatment of cancer is characterized by abundance
of thermal ablative techniques that provide a minimally invasive treatment option in selected …

First human trial of high-frequency irreversible electroporation therapy for prostate cancer

S Dong, H Wang, Y Zhao, Y Sun… - Technology in cancer …, 2018 - journals.sagepub.com
Irreversible electroporation, as a nonthermal therapy of prostate cancer, has been used in
clinic for several years. The mechanism of irreversible electroporation ablation is thermal …

High-frequency irreversible electroporation for intracranial meningioma: a feasibility study in a spontaneous canine tumor model

EL Latouche, CB Arena, JW Ivey… - … in cancer research …, 2018 - journals.sagepub.com
High-frequency irreversible electroporation is a nonthermal method of tissue ablation that
uses bursts of 0.5-to 2.0-microsecond bipolar electric pulses to permeabilize cell …

A theoretical argument for extended interpulse delays in therapeutic high-frequency irreversible electroporation treatments

KN Aycock, Y Zhao, MF Lorenzo… - IEEE Transactions on …, 2021 - ieeexplore.ieee.org
High-frequency irreversible electroporation (H-FIRE) is a tissue ablation modality employing
bursts of electrical pulses in a positive phase–interphase delay (d 1)–negative phase …

MRI and contrast-enhanced ultrasound imaging for evaluation of focal irreversible electroporation treatment: results from a phase I-II study in patients undergoing IRE …

W van den Bos, DM de Bruin, A Van Randen… - European …, 2016 - Springer
Objectives Irreversible electroporation (IRE) is an ablative therapy with a low side-effect
profile in prostate cancer. The objective was: 1) To compare the volumetric IRE ablation …

Effect of focal vs extended irreversible electroporation for the ablation of localized low-or intermediate-risk prostate cancer on early oncological control: a randomized …

K Zhang, J Teoh, P Laguna, J Dominguez-Escrig… - JAMA …, 2023 - jamanetwork.com
Importance Focal ablative irreversible electroporation (IRE) is a therapy that treats only the
area of the tumor with the aim of achieving oncological control while reducing treatment …