Holistic evaluation of a machine learning-based timing calibration for PET detectors under varying data sparsity

S Naunheim, F Mueller, V Nadig, Y Kuhl… - Physics in Medicine …, 2024 - iopscience.iop.org
Objective. Modern PET scanners offer precise TOF information, improving the SNR of the
reconstructed images. Timing calibrations are performed to reduce the worsening effects of …

Scalable, time-of-flight and depth-of-interaction detector units for high-resolution pet systems

V Nadig, S Gundacker, D Schug… - … on Radiation and …, 2023 - ieeexplore.ieee.org
Resolving the depth of interaction (DOI) of a-photon in the scintillator is necessary to correct
for parallax errors in organ-dedicated and large-scale time-of-flight positron emission …

Improving the timing resolution of positron emission tomography detectors using boosted learning—a residual physics approach

S Naunheim, Y Kuhl, D Schug… - IEEE Transactions on …, 2023 - ieeexplore.ieee.org
Artificial intelligence (AI) is entering medical imaging, mainly enhancing image
reconstruction. Nevertheless, improvements throughout the entire processing, from signal …

A finely segmented semi‐monolithic detector tailored for high‐resolution PET

Y Kuhl, F Mueller, S Naunheim, M Bovelett… - Medical …, 2024 - Wiley Online Library
Background Preclinical research and organ‐dedicated applications use and require high
(spatial‐) resolution positron emission tomography (PET) detectors to visualize small …

Design and proof of concept of a double-panel TOF-PET system

A Gonzalez-Montoro, N Pavón, J Barberá, N Cuarella… - EJNMMI physics, 2024 - Springer
Abstract Objective Positron Emission Tomography (PET) is a well-known imaging
technology for the diagnosis, treatment, and monitoring of several diseases. Most PET …

3D in‐system calibration method for PET detectors

Y Kuhl, F Mueller, J Thull, S Naunheim… - Medical …, 2025 - Wiley Online Library
Background Light‐sharing detector designs for positron emission tomography (PET)
systems have sparked interest in the scientific community. Particularly,(semi‐) monoliths …

First results of the 4D-PET brain system

A Gonzalez-Montoro… - … on Radiation and …, 2024 - ieeexplore.ieee.org
Positron Emission Tomography (PET) imaging is the molecular technique of choice for
studying many illnesses, including the ones related to the brain. Nevertheless, the use of …

Design and characterization of a hybrid PET detector with DOI capability

W He, Y Zhao, H Zeng, W Huang, H Yang… - Medical …, 2024 - Wiley Online Library
Background Monolithic or semi‐monolithic detectors are attractive for positron emission
tomography (PET) scanners with depth‐of‐interaction (DOI) capability. However, they often …

Using Residual Physics to reach near-200 ps CTR with TOFPET2 ASIC Readout and Clinical Detector Blocks

S Naunheim, F Mueller, V Nadig, Y Kuhl… - 2024 IEEE Nuclear …, 2024 - ieeexplore.ieee.org
Last year's SNMMI, Siemens Healthineers presented the Biograph Vision. X PET/CT
scanner, currently delivering the industry's leading time-of-flight (TOF). Although recent TOF …

Towards artificial data generation for accelerated PET detector ML-based timing calibration using GANs

K Lavronenko, LL de Paiva, F Mueller… - 2024 IEEE Nuclear …, 2024 - ieeexplore.ieee.org
In PET systems, TOF scanners require dedicated time skew calibration of the individual
detectors, which is commonly performed by analytical approaches. In previous research, we …