Neurodegenerative diseases, such as Alzheimer's disease (AD), are characterized by
massive loss of specific neurons. It is a progressive disabling, severe and fatal complex …

CAD (Carbamoyl-phosphate synthetase 2, Aspartate transcarbamoylase, and
Dihydroorotase) is a multifunctional protein that participates in the initial three speed-limiting …

Rivastigmine, a reversible cholinesterase inhibitor, is frequently indicated in the
management of demented conditions associated with Alzheimer disease. The major hurdle …

Under most conditions, 2, 4-dihalopyrimidines undergo substitution reactions at C4. Here we
report that Pd (II) precatalysts supported by bulky N-heterocyclic carbene ligands uniquely …

Background: Alzheimer's disease is a neurological dysfunction of the brain caused by
neurodegeneration and oxidative stress. Some viruses, such as herpes viruses, HSV-1, and …

IMPHY000797 derivatives have been well known for their efficacy in various diseases.
Moreover, IMPHY000797 derivatives have been found to modulate such genes involved in …

Introduction Alzheimer's disease (AD) is a neurodegenerative disorder that significantly
impacts the cognitive function and memory of a person. Despite the significant research …

Pyrimidine‐based derivatives have attracted a lot of interest in heterocyclic chemistry due to
its versatile structure and diverse biological activities. This study provides a comprehensive …

Alzheimer's disease (AD) is a complex/multifactorial brain disorder involving hundreds of
defective genes, epigenetic aberrations, cerebrovascular alterations, and environmental risk …

Thiourea and its derivatives have become a significant focal point within the organic
synthesis field, garnering attention for their diverse biological applications, including …