The discovery of vascular endothelial-derived growth factor (VEGF) has revolutionized our
understanding of vasculogenesis and angiogenesis during development and physiological …

All solid tumours require a vascular supply in order to progress. Although the ability to
induce angiogenesis (new blood vessel growth) has long been regarded as essential to this …

Background Patients with locoregionally advanced nasopharyngeal carcinoma have a high
risk of disease relapse, despite a high proportion of patients attaining complete clinical …

Over the last seven decades, a significant scientific contribution took place in the delineation
of the implications of vascular endothelial‐derived growth factor (VEGF) in the processes of …

The targeting of vascular endothelial growth factor A (VEGFA), a crucial regulator of both
normal and pathological angiogenesis, has revealed innovative therapeutic approaches in …

Background Bevacizumab plus fluoropyrimidine-based chemotherapy is standard treatment
for first-line and bevacizumab-naive second-line metastatic colorectal cancer. We assessed …

Immunotherapies based on T cells have gained significant success in the treatment of
diverse cancers, however, several limitations also exist, including low response, acquired …

Vinca alkaloids are a subset of drugs obtained from the Madagascar periwinkle plant. They
are naturally extracted from the pink periwinkle plant, Catharanthus roseus G. Don and have …

Vascular endothelial growth factor (VEGF) is a key regulator of physiological angiogenesis
during embryogenesis, skeletal growth and reproductive functions. VEGF has also been …

It has become evident that we cannot understand tumour growth without considering
components of the stromal microenvironment, such as the vasculature. At the same time, the …