Tumor‐associated macrophages in liver cancer: from mechanisms to therapy

K Cheng, N Cai, J Zhu, X Yang, H Liang… - Cancer …, 2022 - Wiley Online Library
Multidimensional analyses have demonstrated the presence of a unique tumor
microenvironment (TME) in liver cancer. Tumor‐associated macrophages (TAMs) are …

[HTML][HTML] Prevention strategies of postoperative adhesion in soft tissues by applying biomaterials: Based on the mechanisms of occurrence and development of …

J Liao, X Li, Y Fan - Bioactive Materials, 2023 - Elsevier
Postoperative adhesion (POA) widely occurs in soft tissues and usually leads to chronic
pain, dysfunction of adjacent organs and some acute complications, seriously reducing …

Breaking through the basement membrane barrier to improve nanotherapeutic delivery to tumours

Q Wang, Q Liang, J Dou, H Zhou, C Zeng, H Pan… - Nature …, 2024 - nature.com
An effective nanotherapeutic transport from the vasculature to the tumour is crucial for
cancer treatment with minimal side effects. Here we demonstrate that, in addition to the …

Kupffer cell–like Syncytia replenish resident macrophage function in the Fibrotic liver

M Peiseler, B Araujo David, J Zindel, BGJ Surewaard… - Science, 2023 - science.org
Kupffer cells (KCs) are localized in liver sinusoids but extend pseudopods to parenchymal
cells to maintain their identity and serve as the body's central bacterial filter. Liver cirrhosis …

Multifunctional microgel-based cream hydrogels for postoperative abdominal adhesion prevention

B Liu, Y Kong, OA Alimi, MA Kuss, H Tu, W Hu… - ACS …, 2023 - ACS Publications
Postoperative abdominal adhesions are a common problem after surgery and can produce
serious complications. Current antiadhesive strategies focus mostly on physical barriers and …

Establishments and evaluations of post‐operative adhesion animal models

Y Wang, W Zhai, L Yang, S Cheng… - Advanced …, 2023 - Wiley Online Library
After abdominopelvic surgery, there are 90–93% of patients who develop postoperative
adhesions. Post‐operative adhesions can occur after various surgical procedures, which not …

Spatiotemporal multiplexed immunofluorescence imaging of living cells and tissues with bioorthogonal cycling of fluorescent probes

J Ko, M Wilkovitsch, J Oh, RH Kohler, E Bolli… - Nature …, 2022 - nature.com
Cells in complex organisms undergo frequent functional changes, but few methods allow
comprehensive longitudinal profiling of living cells. Here we introduce scission-accelerated …

[HTML][HTML] Abdominal wall hernia repair: From prosthetic meshes to smart materials

Q Saiding, Y Chen, J Wang, CL Pereira, B Sarmento… - Materials Today Bio, 2023 - Elsevier
Hernia reconstruction is one of the most frequently practiced surgical procedures worldwide.
Plastic surgery plays a pivotal role in reestablishing desired abdominal wall structure and …

An Injectable Asymmetric‐Adhesive Hydrogel as a GATA6+ Cavity Macrophage Trap to Prevent the Formation of Postoperative Adhesions after Minimally Invasive …

X Wu, W Guo, L Wang, Y Xu, Z Wang… - Advanced Functional …, 2022 - Wiley Online Library
Antiadhesive hydrogels have been developed for preventing the formation of postoperative
adhesions. However, it is challenging to design an injectable hydrogel with superior tissue …

Injectable photocurable Janus hydrogel delivering hiPSC cardiomyocyte-derived exosome for post–heart surgery adhesion reduction

L Wang, P Chen, Y Pan, Z Wang, J Xu, X Wu… - Science …, 2023 - science.org
Postsurgical pericardial adhesions pose increased risks of sequelae, prolonged reoperation
time, and reduced visibility in the surgical field. Here, we introduce an injectable Janus …