The Role of l-Carnitine in Mitochondria, Prevention of Metabolic Inflexibility and Disease Initiation

MA Virmani, M Cirulli - International journal of molecular sciences, 2022 - mdpi.com
Mitochondria control cellular fate by various mechanisms and are key drivers of cellular
metabolism. Although the main function of mitochondria is energy production, they are also …

Obesity: A preventable, treatable, but relapsing disease

A De Lorenzo, L Romano, L Di Renzo, N Di Lorenzo… - Nutrition, 2020 - Elsevier
Abstract In 2013, the American Medical Association recognized obesity as a disease, of
growing scientific, social, and political interest. In 2016 in the United States, prevalence rates …

A randomized controlled trial to isolate the effects of fasting and energy restriction on weight loss and metabolic health in lean adults

I Templeman, HA Smith, E Chowdhury… - Science translational …, 2021 - science.org
Intermittent fasting may impart metabolic benefits independent of energy balance by
initiating fasting-mediated mechanisms. This randomized controlled trial examined 24-hour …

Significance of l‐carnitine for human health

MM Adeva‐Andany, I Calvo‐Castro… - IUBMB …, 2017 - Wiley Online Library
Carnitine acyltransferases catalyze the reversible transfer of acyl groups from acyl‐
coenzyme A esters to l‐carnitine, forming acyl‐carnitine esters that may be transported …

Role of carnitine and its derivatives in the development and management of type 2 diabetes

J Bene, K Hadzsiev, B Melegh - Nutrition & diabetes, 2018 - nature.com
Type 2 diabetes is a highly prevalent chronic metabolic disorder characterized by
hyperglycemia and associated with several complications such as retinopathy …

[图书][B] Handbook of Obesity--Volume 1: Epidemiology, Etiology, and Physiopathology

GA Bray - 2014 - books.google.com
In recent years, we've developed a much better grasp of the biological and other factors
associated with the development of obesity. Reflecting our evolving understanding of …

Antioxidants in the treatment of diabetes

S Golbidi, S Alireza Ebadi, I Laher - Current diabetes reviews, 2011 - ingentaconnect.com
Diabetes is a chronic metabolic disorder that continues to present as a major health problem
worldwide. It is characterized by absolute or relative deficiencies in insulin secretion and/or …

Role of carnitine in the regulation of glucose homeostasis and insulin sensitivity: evidence from in vivo and in vitro studies with carnitine supplementation and carnitine …

R Ringseis, J Keller, K Eder - European journal of nutrition, 2012 - Springer
Background Although carnitine is best known for its role in the import of long-chain fatty
acids (acyl groups) into the mitochondrial matrix for subsequent β-oxidation, carnitine is also …

[HTML][HTML] L-carnitine treatment of insulin resistance: A systematic review and meta-analysis

Y Xu, W Jiang, G Chen, W Zhu, W Ding… - … in Clinical and …, 2017 - advances.umw.edu.pl
Background. L-carnitine has been used for several years as an adjuvant therapy in oxidative
stress, blood sugar, high-sensitivity C-reactive protein (CRP), anemia, etc. However, the …

Expression of Concern: Oral carnitine supplementation reduces body weight and insulin resistance in women with polycystic ovary syndrome: a randomized, double …

M Samimi, M Jamilian, FA Ebrahimi… - Clinical …, 2016 - Wiley Online Library
Objective Limited data are available for evaluating the effects of oral carnitine
supplementation on weight loss and metabolic profiles of women with polycystic ovary …