Arthritogenic alphaviruses—an overview

A Suhrbier, MC Jaffar-Bandjee, P Gasque - Nature Reviews …, 2012 - nature.com
Mosquito-transmitted alphaviruses causing human rheumatic disease are globally
distributed and include chikungunya virus, Ross River virus, Barmah Forest virus, Sindbis …

Fc receptors in antibody‐dependent enhancement of viral infections

A Taylor, SS Foo, R Bruzzone, L Vu Dinh… - Immunological …, 2015 - Wiley Online Library
Sensitization of the humoral immune response to invading viruses and production of
antiviral antibodies forms part of the host antiviral repertoire. Paradoxically, for a number of …

Chikungunya virus arthritis in adult wild-type mice

J Gardner, I Anraku, TT Le, T Larcher, L Major… - Journal of …, 2010 - Am Soc Microbiol
Chikungunya virus is a mosquito-borne arthrogenic alphavirus that has recently reemerged
to produce the largest epidemic ever documented for this virus. Here we describe a new …

Viral-induced enhanced disease illness

MK Smatti, AA Al Thani, HM Yassine - Frontiers in microbiology, 2018 - frontiersin.org
Understanding immune responses to viral infections is crucial to progress in the quest for
effective infection prevention and control. The host immunity involves various mechanisms to …

Chikungunya disease: infection-associated markers from the acute to the chronic phase of arbovirus-induced arthralgia

L Dupuis-Maguiraga, M Noret, S Brun… - PLoS neglected …, 2012 - journals.plos.org
At the end of 2005, an outbreak of fever associated with joint pain occurred in La Réunion.
The causal agent, chikungunya virus (CHIKV), has been known for 50 years and could thus …

Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays

L Pohjala, A Utt, M Varjak, A Lulla, A Merits, T Ahola… - PloS one, 2011 - journals.plos.org
Chikungunya virus (CHIKV), an alphavirus, has recently caused epidemic outbreaks and is
therefore considered a re-emerging pathogen for which no effective treatment is available. In …

The acute phase of Chikungunya virus infection in humans is associated with strong innate immunity and T CD8 cell activation

N Wauquier, P Becquart, D Nkoghe… - Journal of Infectious …, 2011 - academic.oup.com
Background. Rapidly spreading to new regions, including the islands of the Indian Ocean,
Central Africa, and Europe, Chikungunya fever is becoming a major problem of public …

Chikungunya: a potentially emerging epidemic?

MM Thiboutot, S Kannan, OU Kawalekar… - PLoS neglected …, 2010 - journals.plos.org
Chikungunya virus is a mosquito-borne emerging pathogen that has a major health impact
in humans and causes fever disease, headache, rash, nausea, vomiting, myalgia, and …

Sindbis virus as a human pathogen—epidemiology, clinical picture and pathogenesis

S Adouchief, T Smura, J Sane… - Reviews in medical …, 2016 - Wiley Online Library
Sindbis virus (SINV; family Togaviridae, genus Alphavirus) is an enveloped RNA virus
widely distributed in Eurasia, Africa, Oceania and Australia. SINV is transmitted among its …

RNA-Seq analysis of chikungunya virus infection and identification of granzyme A as a major promoter of arthritic inflammation

JAC Wilson, NA Prow, WA Schroder, JJ Ellis… - PLoS …, 2017 - journals.plos.org
Chikungunya virus (CHIKV) is an arthritogenic alphavirus causing epidemics of acute and
chronic arthritic disease. Herein we describe a comprehensive RNA-Seq analysis of feet …