Exposure to stress is an undeniable, but in most cases surmountable, part of life. However,
in certain individuals, exposure to severe or cumulative stressors can lead to an array of …

Cannabis is the most widely used illicit drug worldwide, though it is unclear whether its
regular use is associated with persistent alterations in brain morphology. This review …

Cannabis derivatives are among the most widely used illicit substances among young
people. The addictive potential of delta-9-tetrahydrocannabinol (THC), the major active …

Introduction: Excessive abdominal obesity along with other risk factors results in the
metabolic syndrome, which can lead to heart disease, Type-2 diabetes, and death. The …

Drug addiction is a major public health concern in the United States costing taxpayers
billions in health care costs, lost productivity and law enforcement. However, the availability …

The hypothalamus–pituitary–adrenal-axis is strongly controlled by the endocannabinoid
system. The specific impact of enhanced 2-arachidonoylglycerol signaling on corticosterone …

Cannabis use is increasing among some demographics in the United States and is tightly
linked to anxiety, trauma, and stress reactivity at the epidemiological and biological level …

The endocannabinoid system plays a key role in the control of emotional responses to
environmental challenges. CB1 receptors are highly expressed within cortico-limbic brain …

Rimonabant, the prototypic antagonist of cannabinoid CB1 receptors, has been reported to
have inverse agonist properties at higher concentrations, which may complicate its use as a …

Objective: To determine the effects of marijuana on athletic performance. Design: We
searched MEDLINE, EMBASE, CINAHL, PsycINFO, AMED, and SPORTDiscus from their …