A restrictive cardiomyopathy mutation in an invariant proline at the myosin head/rod junction enhances head flexibility and function, yielding muscle defects in …
M Achal, AS Trujillo, GC Melkani, GP Farman… - Journal of molecular …, 2016 - Elsevier
An “invariant proline” separates the myosin S1 head from its S2 tail and is proposed to be
critical for orienting S1 during its interaction with actin, a process that leads to muscle …
critical for orienting S1 during its interaction with actin, a process that leads to muscle …
Finding the candidate sequence variants for diagnosis of hypertrophic cardiomyopathy in East Slovak patients
M Zigova, J Bernasovska, I Boronova… - Journal of Clinical …, 2018 - Wiley Online Library
Background Hypertrophic cardiomyopathy is a heterogeneous myocardial disease.
Mutations appearing in several genes might be a potential cause of the disease. The aim of …
Mutations appearing in several genes might be a potential cause of the disease. The aim of …