Growth factors play a crucial role in tissue engineering by directing the fate of cells and
allowing the formation of tissues. Understanding the key requirements for growth factor …

Soft tissue damage is a common clinical problem that affects the lives of a large number of
patients all over the world. It is of great importance to develop functional scaffolds to …

Antioxidant is critical for the successful of nerve tissue regeneration, and biomaterials with
antioxidant activity might be favorable for peripheral nerve repair. Lignin, a biopolymer from …

The dura mater provides a barrier to protect the tissue underneath and cerebrospinal fluid.
However, dural defects normally cause cerebrospinal fluid leakage and other complications …

Dural defects are a common problem in neurosurgical procedures and should be repaired to
avoid complications such as cerebrospinal fluid leakage, brain swelling, epilepsy …

Recent work demonstrated that 3D fibrin scaffolds function as an effective substrate for
engineering tissues from pluripotent stem cells. However, the rapid degradation rate of fibrin …

Understanding the relevant biophysical properties of the spinal dura mater is essential to the
design of medical devices that will directly interact with this membrane or influence the …

The central nervous system (CNS) has a highly complex biophysical and biochemical
environment. Despite decades of intensive research, it is still an enormous challenge to …

Human pluripotent stem cells (hPSCs), including embryonic stem cells (hESCs) and induced
pluripotent stem cells (hiPSCs), have the potential to differentiate into many cell types that …

There is currently no cure for individuals with spinal cord injury (SCI). While many promising
approaches are being tested in clinical trials, the complexity of SCI limits several of these …