Advanced good cell culture practice for human primary, stem cell-derived and organoid models as well as microphysiological systems

D Pamies, AK Bal-Price, C Chesné, S Coecke… - 2018 - kops.uni-konstanz.de
A major reason for the current reproducibility crisis in the life sciences is the poor
implementation of quality control measures and reporting standards. Improvement is …

Application of RPTEC/TERT1 cells for investigation of repeat dose nephrotoxicity: a transcriptomic study

L Aschauer, A Limonciel, A Wilmes, S Stanzel… - Toxicology in Vitro, 2015 - Elsevier
The kidney is a major target organ for toxicity. Incidence of chronic kidney disease (CKD) is
increasing at an alarming rate due to factors such as increasing population age and …

Differentiation and Subculturing of Renal Proximal Tubular‐like Cells Derived from Human iPSC

T Meijer, E Naderlinger, P Jennings… - Current protocols, 2023 - Wiley Online Library
Recently, we have developed a protocol to differentiate human induced pluripotent stem
cells (iPSC) into proximal tubular‐like cells (PTL)(Chandrasekaran et al., 2021). These cells …

Ensuring the Quality of Stem Cell-Derived In Vitro Models for Toxicity Testing

GN Stacey, S Coecke, AB Price, L Healy… - Validation of Alternative …, 2016 - Springer
Quality control of cell cultures used in new in vitro toxicology assays is crucial to the
provision of reliable, reproducible and accurate toxicity data on new drugs or constituents of …

[HTML][HTML] 低氧诱导因子-1α 对牦牛肾小管上皮细胞上皮-间质转化的影响

白雪峰, 崔燕, 余四九, 李慧, 何俊峰, 廖博 - 畜牧兽医学报, 2020 - html.rhhz.net
本研究旨在探讨低氧诱导因子-1α (HIF-1α) 对牦牛肾小管上皮细胞上皮-间质转化(EMT) 的影响.
首先对牦牛肾小管上皮细胞进行培养鉴定, 并选取第三代细胞对其分别进行药物处理(DMOG 组) …