[HTML][HTML] Targeting apoptosis in MCF-7 and Ehrlich ascites carcinoma cells by saponifiable fractions from green and black Vitis vinifera seed oil

NZ Shaban, AA El-Faham, MM Abu-Serie… - Biomedicine & …, 2023 - Elsevier
Grape seed (GS) oil is one of the potential functional foods. For the first time, we evaluated
the therapeutic effects of GS oil saponifiable (Sap)-fraction from black (BSap) and green …

[HTML][HTML] The black Vitis vinifera seed oil saponifiable fraction ameliorates hepatocellular carcinoma in vitro and in vivo via modulating apoptosis and ROS/NF-κB …

NZ Shaban, AA El-Faham, MM Abu-Serie… - Biomedicine & …, 2024 - Elsevier
To date, no total curative therapy for hepatocellular carcinoma (HCC) is available. This study
aimed to evaluate the anticancer effect of black Vitis vinifera (VV) seed oil saponifiable (Sap) …

Structure-based drug design of DNA minor groove binders and evaluation of their antibacterial and anticancer properties

HY Alniss, HM Al-Jubeh, YA Msallam, R Siddiqui… - European Journal of …, 2024 - Elsevier
Antimicrobial and chemotherapy resistance are escalating medical problem of paramount
importance. Yet, research for novel antimicrobial and anticancer agents remains lagging …

Peptide-functionalized zinc oxide nanoparticles for the selective targeting of breast cancer expressing placenta-specific protein 1

R Cagliani, B Fayed, J Jagal, SB Shakartalla… - Colloids and Surfaces B …, 2023 - Elsevier
Functionalized metal oxide nanoparticles (NPs) have demonstrated specific binding affinity
to antigens or receptors presented on the cancer cell surface, favouring selective targeting …

[HTML][HTML] Iterated virtual screening-assisted antiviral and enzyme inhibition assays reveal the discovery of novel promising anti-SARS-CoV-2 with dual activity

R Hamdy, B Fayed, A Mostafa, NMA Shama… - International Journal of …, 2021 - mdpi.com
Unfortunately, COVID-19 is still a threat to humankind and has a dramatic impact on human
health, social life, the world economy, and food security. With the limited number of …

[HTML][HTML] Comparative metabolomics reveals the microenvironment of common T-helper cells and differential immune cells linked to unique periapical lesions

AM Altaie, T Venkatachalam… - Frontiers in …, 2021 - frontiersin.org
Periapical abscesses, radicular cysts, and periapical granulomas are the most frequently
identified pathological lesions in the alveolar bone. While little is known about the initiation …

[HTML][HTML] 1H-NMR metabolomics analysis identifies hypoxanthine as a novel metastasis-associated metabolite in breast cancer

SB Shakartalla, NS Ashmawy, MH Semreen… - Scientific Reports, 2024 - nature.com
Breast cancer is one of the leading causes of death in females, mainly because of
metastasis. Oncometabolites, produced via metabolic reprogramming, can influence …

[HTML][HTML] Estimating the viral loads of SARS-CoV-2 in the oral cavity when complicated with periapical lesions

AM Altaie, R Hamdy, T Venkatachalam, R Hamoudi… - BMC Oral Health, 2021 - Springer
Background The oral cavity represents a main entrance of the severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2). Angiotensin-converting enzyme 2 (ACE-2) …

Identification of phytochemicals capping the exogenously biosynthesized silver nanoparticles by T. apollinea (Delile) DC. living plants and evaluation of their cytotoxic …

MA Ali, SSM Soliman, K Bajou, A El-Keblawy… - Biocatalysis and …, 2022 - Elsevier
The exogenous synthesis of nanoparticles (NPs) by living plant systems was considered a
sustainable way to synthesize NPs. It is cost-effective and more eco-friendly compared to the …

[HTML][HTML] Changes in the gut microbiota of NOD mice in response to an oral Salmonella-based vaccine against type 1 diabetes

J Cobb, SSM Soliman, M Retuerto, JC Quijano, C Orr… - Plos one, 2023 - journals.plos.org
We developed an oral Salmonella-based vaccine that prevents and reverses diabetes in
non-obese diabetic (NOD) mice. Related to this, the gastrointestinal tract harbors a complex …