Background: Adipose tissue defects leading to severe functional (disability) and
morphologic (disfigurement) morbidity are often treated in plastic surgery with fat grafting …

Background Free flap reconstruction after lower extremity trauma remains challenging with
various factors affecting overall success. Increasing defect and flap size have been …

Negative-pressure wound therapy (NPWT) promotes wound healing by applying negative
pressure to the wound surface. A quarter of a century after its introduction, NPWT has been …

Background: Perforator flaps are commonly applied for a variety of skin defects. Many
strategies (eg, hyperbaric oxygen and preconditioning) have been investigated to improve …

Background Although autologous fat grafting (AFG) for breast reconstruction is feasible, the
best methods have yet to be established. This study aimed to assess the efficacy of fat …

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Summary Background Endothelial progenitor cells (EPCs) are one type of bone marrow
hematopoietic stromal cells which play a vital role in neovascularization and tissue repair. In …

Background Multi-territory perforator flaps have become the preferred option for the repair
and reconstruction of large soft tissue defects. Although methods (eg, pharmacological …

Background Ischemic preconditioning of the forehead flap prior to pedicle division helps to
improve angiogenesis. Clamping the pedicle by a clamped rubber band with vessel forceps …

Negative pressure therapy has been utilized in the treatment of open and closed wounds to
increase blood flow and improve wound healing. More recently, external negative pressure …