Protein posttranslational modifications (PTMs) refer to the breaking or generation of covalent
bonds on the backbones or amino acid side chains of proteins and expand the diversity of …

Protein O-glycosylation is widely identified in various proteins involved in diverse biological
processes. Recent studies have demonstrated that O-glycosylation plays crucial and …

The modification of intracellular proteins with O-linked β-N-acetylglucosamine (O-GlcNAc)
moieties is a highly dynamic process that spatiotemporally regulates nearly every important …

Cell cycle errors can lead to mutations, chromosomal instability, or death; thus, the precise
control of cell cycle progression is essential for viability. The nutrient-sensing post …

Proteins are ubiquitously modified with glycans of varied chemical structures through distinct
glycosidic linkages, making the landscape of protein glycosylation challenging to map …

Abstract O-linked-N-acetylglucosaminylation (O-GlcNAcylation), a dynamic post-
translational modification (PTM), holds profound implications in controlling various cellular …

O-GlcNAcylation is involved in many biological processes including cancerization.
Nevertheless, its in situ quantification in single living cells is still a bottleneck. Here we …

Protein glycosylation is one of the most common and important post-translational
modifications of proteins involved in regulating glycoprotein functions. The chemoenzymatic …

O-Linked β-N-acetylglucosamine (O-GlcNAc) is an essential, dynamic monosaccharide post-
translational modification (PTM) found on serine and threonine residues of thousands of …

The transport of proteins between the different cellular compartments and the cell surface is
governed by the secretory pathway. Alternatively, unconventional secretion pathways have …