Adaptation to fluctuations in nutrient availability is a fact of life for single-celled organisms in
the'wild'. A decade ago our understanding of how bacteria adjust cell cycle parameters to …

The replication origin and the initiator protein DnaA are the main targets for regulation of
chromosome replication in bacteria. The origin bears multiple DnaA binding sites, while …

Aerobic glycolysis is defined as glucose utilization in excess of that used for oxidative
phosphorylation despite sufficient oxygen to completely metabolize glucose to carbon …

Glycolysis is one of the most important metabolic pathways in heterotrophic organisms.
Several genes encoding glycolytic enzymes are essential in many bacteria even under …

Background Fluctuations in temperature occur naturally during plant growth and
reproduction. However, in the hot summers this variation may become stressful and …

Glycerol is one of the few carbon sources that can be utilized by Mycoplasma pneumoniae.
Glycerol metabolism involves uptake by facilitated diffusion, phosphorylation, and the …

Highlights•Bacterial size and chemical composition are thought to be growth rate-
dependent.•The correlation between growth rate and size is affected by nutrient …

Cell division in bacteria is driven by a cytoskeletal ring structure, the Z ring, composed of
polymers of the tubulin-like protein FtsZ. Z-ring formation must be tightly regulated to ensure …

All regulatory processes require components that sense the environmental or metabolic
conditions of the cell, and sophisticated sensory proteins have been studied in great detail …

Genetic, biochemical, pathological, and biomarker data demonstrate that Alzheimer's
disease (AD) pathology, including the initiation and progressive buildup of insoluble forms of …