Diagnosis and treatment of candidemia in the intensive care unit

M Bassetti, DR Giacobbe, A Vena… - Seminars in respiratory …, 2019 - thieme-connect.com
Candidemia is the fourth most frequent health care-associated bloodstream infection, and
the most frequent severe fungal infection developing in critically ill patients in intensive care …

Aspergillus test profiles and mortality in critically ill COVID-19 patients

M Ergün, RJM Brüggemann, A Alanio… - Journal of clinical …, 2021 - Am Soc Microbiol
The literature regarding COVID-19-associated pulmonary aspergillosis (CAPA) has shown
conflicting observations, including survival of CAPA patients not receiving antifungal therapy …

Bloodstream infections in internal medicine

V Del Bono, DR Giacobbe - Virulence, 2016 - Taylor & Francis
Bloodstream infections (BSI) carry a heavy burden of morbidity and mortality in modern
internal medicine wards (IMW). These wards are often filled with elderly subjects with …

Combined use of serum (1,3)-β-d-glucan and procalcitonin for the early differential diagnosis between candidaemia and bacteraemia in intensive care units

DR Giacobbe, M Mikulska, M Tumbarello, E Furfaro… - Critical Care, 2017 - Springer
Background This study aimed to assess the combined performance of serum (1, 3)-β-d-
glucan (BDG) and procalcitonin (PCT) for the differential diagnosis between candidaemia …

Prospective evaluation of serum β-glucan testing in patients with probable or proven fungal diseases

C Angebault, F Lanternier, F Dalle… - Open forum …, 2016 - academic.oup.com
Background. Early diagnosis and treatment are crucial in invasive fungal diseases (IFD).
Serum (1-3)-β-d-glucan (BG) is believed to be an early IFD marker, but its diagnostic …

The Pitt Bacteremia Score, Charlson Comorbidity Index and Chronic Disease Score are useful tools for the prediction of mortality in patients with Candida …

MP Vaquero‐Herrero, S Ragozzino… - Mycoses, 2017 - Wiley Online Library
Candida bloodstream infection (CBI) is associated with high mortality. The aim of this study
was to compare the utility of the combined use of the Pitt Bacteremia Score (PBS) and …

Prognostic value of serial (1,3)-β-d-glucan measurements in ICU patients with invasive candidiasis

S Carelli, B Posteraro, R Torelli, E De Carolis… - Critical Care, 2024 - Springer
Background To determine whether a decrease in serum (1, 3)-β-d-glucan (BDG) was
associated with reduced mortality and to investigate the performance of BDG downslope in …

Risk factors associated with mortality among patients who had candidemia in a university hospital

PGV Alves, SGO Melo, MAS Bessa, MO Brito… - Revista da Sociedade …, 2020 - SciELO Brasil
INTRODUCTION: Bloodstream infection due to Candida spp. is a primary cause of morbidity
and mortality in tertiary hospitals. METHODS: In this retrospective study, we included …

Interaction Between Dendritic Cells and Candida krusei β-Glucan Partially Depends on Dectin-1 and It Promotes High IL-10 Production by T Cells

TTH Dinh, P Tummamunkong, P Padungros… - Frontiers in cellular …, 2021 - frontiersin.org
Host-Candida interaction has been broadly studied during Candida albicans infection, with
a progressive shift in focus toward non-albicans Candida species. C. krusei is an emerging …

Use of 1, 3-β-D-glucan in invasive fungal diseases in hematology patients

DR Giacobbe, V Del Bono, C Viscoli… - Expert Review of Anti …, 2017 - Taylor & Francis
Introduction: Invasive fungal diseases (IFD) remain a leading cause of morbidity and
mortality in hematology patients. Within a diagnostic-driven approach, the use of the serum …