Multiphoton FLIM analyses of native and UVA-modified synthetic melanins

AM Pena, S Ito, T Bornschlögl, S Brizion… - International Journal of …, 2023 - mdpi.com
To better understand the impact of solar light exposure on human skin, the chemical
characterization of native melanins and their structural photo-modifications is of central …

Fluorescence lifetime sorting reveals tunable enzyme interactions within cytoplasmic condensates

LE Fahim, JM Marcus, ND Powell, ZA Ralston… - Journal of Cell …, 2024 - rupress.org
Ribonucleoprotein (RNP) condensates partition RNA and protein into multiple liquid phases.
The multiphasic feature of condensate-enriched components creates experimental …

Pioglitazone Phases and Metabolic Effects in Nanoparticle-Treated Cells Analyzed via Rapid Visualization of FLIM Images

B Todaro, L Pesce, F Cardarelli, S Luin - Molecules, 2024 - mdpi.com
Fluorescence lifetime imaging microscopy (FLIM) has proven to be a useful method for
analyzing various aspects of material science and biology, like the supramolecular …

Investigating the relationship between hypoxia, hypoxia-inducible factor 1, and the optical redox ratio in response to radiation therapy

JD Ivers, N Puvvada, CM Quick… - Biophotonics …, 2024 - spiedigitallibrary.org
Significance Radiation resistance is a major contributor to cancer treatment failure and is
likely driven by multiple pathways. Multivariate visualization that preserves the spatial co …

FLIMPA: A versatile software for Fluorescence Lifetime Imaging Microscopy Phasor Analysis

S Kapsiani, NF Läubli, EN Ward, M Shehata… - bioRxiv, 2024 - biorxiv.org
Fluorescence lifetime imaging microscopy (FLIM) is an advanced microscopy technique
capable of providing a deeper understanding of the molecular environment of a fluorophore …