Current state of fabrication technologies and materials for bone tissue engineering

A Wubneh, EK Tsekoura, C Ayranci, H Uludağ - Acta Biomaterialia, 2018 - Elsevier
A range of traditional and free-form fabrication technologies have been investigated and, in
numerous occasions, commercialized for use in the field of regenerative tissue engineering …

Role of implants surface modification in osseointegration: A systematic review

Y Liu, B Rath, M Tingart… - Journal of Biomedical …, 2020 - Wiley Online Library
Long‐term and stable fixation of implants is one of the most important points for a successful
orthopedic surgery in the field of endoprosthesis. Osseointegration (OI), functional …

Additively manufactured scaffolds for bone tissue engineering and the prediction of their mechanical behavior: A review

XY Zhang, G Fang, J Zhou - Materials, 2017 - mdpi.com
Additive manufacturing (AM), nowadays commonly known as 3D printing, is a revolutionary
materials processing technology, particularly suitable for the production of low-volume parts …

In vitro and in vivo study of additive manufactured porous Ti6Al4V scaffolds for repairing bone defects

G Li, L Wang, W Pan, F Yang, W Jiang, X Wu, X Kong… - Scientific reports, 2016 - nature.com
Metallic implants with a low effective modulus can provide early load-bearing and reduce
stress shielding, which is favorable for increasing in vivo life-span. In this research, porous …

[HTML][HTML] Complex geometry and integrated macro-porosity: Clinical applications of electron beam melting to fabricate bespoke bone-anchored implants

A Palmquist, M Jolic, E Hryha, FA Shah - Acta biomaterialia, 2023 - Elsevier
The last decade has witnessed rapid advancements in manufacturing technologies for
biomedical implants. Additive manufacturing (or 3D printing) has broken down major …

Commercially pure titanium (cp-Ti) versus titanium alloy (Ti6Al4V) materials as bone anchored implants—Is one truly better than the other?

FA Shah, M Trobos, P Thomsen, A Palmquist - Materials Science and …, 2016 - Elsevier
Commercially pure titanium (cp-Ti) and titanium alloys (typically Ti6Al4V) display excellent
corrosion resistance and biocompatibility. Although the chemical composition and …

Biological strategies for improved osseointegration and osteoinduction of porous metal orthopedic implants

EA Lewallen, SM Riester, CA Bonin… - … Engineering Part B …, 2015 - liebertpub.com
The biological interface between an orthopedic implant and the surrounding host tissue may
have a dramatic effect upon clinical outcome. Desired effects include bony ingrowth …

Long-term osseointegration of 3D printed CoCr constructs with an interconnected open-pore architecture prepared by electron beam melting

FA Shah, O Omar, F Suska, A Snis, A Matic… - Acta biomaterialia, 2016 - Elsevier
In orthopaedic surgery, cobalt chromium (CoCr) based alloys are used extensively for their
high strength and wear properties, but with concerns over stress shielding and bone …

Long-term biocompatibility and osseointegration of electron beam melted, free-form–fabricated solid and porous titanium alloy: Experimental studies in sheep

A Palmquist, A Snis, L Emanuelsson… - Journal of …, 2013 - journals.sagepub.com
The purpose of the present study was to evaluate the long-term osseointegration and
biocompatibility of electron beam melted (EBM) free-form–fabricated (FFF titanium grade 5 …

A review on in vitro/in vivo response of additively manufactured Ti–6Al–4V alloy

S Alipour, S Nour, SM Attari, M Mohajeri… - Journal of Materials …, 2022 - pubs.rsc.org
Bone replacement using porous and solid metallic implants, such as Ti-alloy implants, is
regarded as one of the most practical therapeutic approaches in biomedical engineering …