[HTML][HTML] Chemical Constituents from Croton Species and Their Biological Activities

WH Xu, WY Liu, Q Liang - Molecules, 2018 - mdpi.com
The genus Croton belongs to the Euphorbiaceae family, which comprises approximately
1300 species. Many Croton species have been used as folk medicines. This review focuses …

A review of biological activities and phytochemistry of six ethnomedicinally important South African Croton species

MP Moremi, F Makolo, AM Viljoen… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance The genus Croton (Euphorbiaceae)
encompasses 1300 species, which consist of a variety of trees and shrubs distributed across …

[HTML][HTML] In vitro and in vivo anti-malarial activity of plants from the Brazilian Amazon

RBS Lima, LF Rocha e Silva, MRS Melo, JS Costa… - Malaria journal, 2015 - Springer
Background The anti-malarials quinine and artemisinin were isolated from traditionally used
plants (Cinchona spp. and Artemisia annua, respectively). The synthetic quinoline anti …

Diterpenoids from the roots of Croton dichogamus Pax

A Aldhaher, M Langat, B Ndunda, D Chirchir… - Phytochemistry, 2017 - Elsevier
Four previously undescribed diterpenoids including two crotofolanes, crotodichogamoin A
and B, and two halimanes, crothalimene A and B, a new sesquiterpenoid, and fifteen …

In Vitro Cytotoxicity and Anti-HIV Activity of Crude Extracts of Croton macrostachyus, Croton megalocarpus and Croton dichogamus

EM Terefe, FA Okalebo, S Derese… - Journal of …, 2021 - Taylor & Francis
Introduction Human immunodeficiency virus (HIV) affects the body's defense mechanisms
and leads to a number of opportunistic infections which later cause fatality as a result of an …

Ent-abietane and ent-pimarane diterpenoids from Croton mubango (Euphorbiaceae)

SM Isyaka, MK Langat, E Mas-Claret, BM Mbala… - Phytochemistry, 2020 - Elsevier
Twelve ent-abietane and two ent-pimarane diterpenoids were isolated from the leaves of
Croton mubango Müll. Arg.(Euphorbiaceae) collected in the Democratic Republic of the …

[HTML][HTML] Synthesis, in vitro antimalarial activity and in silico studies of hybrid kauranoid 1, 2, 3-triazoles derived from naturally occurring diterpenes

JO Santos, GR Pereira, GC Brandão… - Journal of the Brazilian …, 2016 - SciELO Brasil
We herein report the synthesis of hybrid kauranoid molecules of type 1, 2, 3-triazole-1, 4-
disubstituted aiming to improve the antimalarial activity of kaurenoic and xylopic acids. The …

[HTML][HTML] Southern Africa as a 'cradle of incense'in wider African aromatherapy

NJ Sadgrove - Scientific African, 2020 - Elsevier
The modern paradigm of aromatherapy is based on in vitro assays of pure volatile organic
compounds (as an essential oil), with activity at non-clinically significant concentrations. Yet …

Ent-clerodane and ent-trachylobane diterpenoids from Croton dictyophlebodes

JJE Munissi, SM Isyaka, E Mas-Claret, M Brabner… - Phytochemistry, 2020 - Elsevier
The stem bark and root bark extracts of Croton dictyophlebodes (Euphorbiaceae) yielded
seven undescribed ent-clerodanes: 15, 16-epoxy-17, 12 (S)-olide-ent-cleroda-1, 3, 13 (16) …

New ent-clerodane and abietane diterpenoids from the roots of Kenyan Croton megalocarpoides Friis & MG Gilbert

B Ndunda, MK Langat, DA Mulholland… - Planta …, 2016 - thieme-connect.com
The roots of the endangered medicinal plant Croton megalocarpoides collected in Kenya
were investigated and twenty-two compounds isolated. Among them were twelve new ent …