N-nitrosodin-propylamine is an organic compound mainly used in organic synthesis. As a
typical pollutant, the accidental release of N-nitrosodin-propylamine may cause …

Objective The incidence of non-alcoholic fatty liver disease is increasing every year, and
there is growing evidence that metabolites and intestinal bacteria play a causal role in …

Acute kidney injury, which is associated with high levels of morbidity and mortality, affects a
significant number of individuals, and can be triggered by multiple factors, such as …

To address the challenge of limited throughput with traditional toxicity testing, a newly
developed high-throughput transcriptomics (HTT) platform, together with a 5-day in vivo rat …

Due to continuous application as a flavoring agent in the pesticide, pharmaceutical, and
food industries, methyl eugenol (ME) persists in the environment and causes deleterious …

To study the complex processes involved in liver injuries, researchers rely on animal
investigations, using chemically or surgically induced liver injuries, to extrapolate findings …

ADB-BUTINACA, as a new psychoactive substance, can induce physical and psychological
dependence. However, the systemic biological impact of ADB-BUTINACA on hepatic …

Purpose We designed this study to investigate the potential correlations between gut
microbiota compositions and hepatic metabolomic disorders in mice with methotrexate …

In recent years, many reports focus on the hepatotoxicity of Gynura segetum root extract
(GSrE), but the interaction between GSrE and the gut microbiota is still unclear. This study …

目的从代谢组学层面探索补骨脂肝损伤机制, 筛选相关生物标志物及代谢通路.
方法采用尾静脉注射脂多糖(LPS) 法建立特异质肝损伤模型, 实验动物随机分为对照组(CMC …