Background Several genome‐wide association studies have revealed a genetic background
with respect to susceptibility to rheumatoid arthritis (RA). Although several individual case …

Signal transducer and activator of transcription 4 (STAT4) is a member of the STAT family,
which is a group of transcription factors that regulate cytokine signaling. Genetic …

Background Rheumatoid arthritis (RA) is a common autoimmune disease with a complex
genetic background. The genes encoding protein tyrosine phosphatase non-receptor type …

Objectives The present study aimed to detect a possible association between PTPN22 gene
polymorphisms and rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) in a …

Background: STAT4 is a transcription factor that plays a role in various cytokine signaling
pathways and in T cell subsets differentiation. Several studies have reported STAT4 gene …

Background Rheumatoid arthritis (RA) is a systemic autoimmune disease with chronic
inflammation. Its pathogenesis involves immunological, genetic, and environmental factors …

The results on associations of tumor necrosis factor (TnF)-receptor associated factor
1/complement component 5 (TRaF1/C5) rs10818488 and rs3761847 polymorphisms with …

Background: Psoriasis is an autoimmune disease with genetic and environmental factors.
Based on the roles of STATs (signaling transducers and activators of transcription) in …

Gout is a self-limiting, auto-inflammatory arthritis induced by the deposition of monosodium
urate crystals in the synovial fluid and periarticular tissues. The aim of this study was to …

Background: Regarding the leukocytes infiltration into the synovium of Rheumatoid Arthritis
(RA) patients is mostly mediated by chemokine ligands and receptors, and following the …