[HTML][HTML] Lipolysis inhibition as a treatment of clinical ketosis in dairy cows: Effects on adipose tissue metabolic and immune responses

M Chirivi, D Cortes, CJ Rendon, GA Contreras - Journal of Dairy Science, 2024 - Elsevier
Dairy cows with clinical ketosis (CK) exhibit excessive adipose tissue (AT) lipolysis and
systemic inflammation. Lipolysis in cows can be induced by the canonical (hormonally …

Investigating circulating miRNA in transition dairy cows: What miRNAomics tells about metabolic adaptation

A Veshkini, HM Hammon, B Lazzari, L Vogel… - Frontiers in …, 2022 - frontiersin.org
In the current study, we investigated dairy cows' circulating microRNA (miRNA) expression
signature during several key time points around calving, to get insights into different aspects …

[HTML][HTML] Gain and loss of subcutaneous and abdominal adipose tissue depot mass of German Holstein dairy cows with different body conditions during the transition …

G Szura, S Schäfers, D von Soosten, U Meyer… - Journal of dairy …, 2020 - Elsevier
Subcutaneous adipose tissue (SCAT) and abdominal adipose tissue (AAT) depots are
mobilized during the fresh cow period (FCP) and early lactation period (ELP) to counteract …

Effect of precalving body condition score on insulin signaling and hepatic inflammatory state in grazing dairy cattle

E Angeli, D Barcarolo, L Durante, G Santiago… - Domestic Animal …, 2021 - Elsevier
During postpartum, high-production dairy cows show a temporary period of insulin
resistance, during which glucose uptake by peripheral tissues is reduced to prioritize milk …

Ceramide metabolism associated with chronic dietary nutrient surplus and diminished insulin sensitivity in the liver, muscle, and adipose tissue of cattle

Á Kenéz, SC Bäßler, E Jorge-Smeding… - Frontiers in …, 2022 - frontiersin.org
High dietary energy and protein supply is common practice in livestock nutrition, aiming to
maximize growth and production performance. However, a chronic nutritional surplus …

Effects of biotin and nicotinamide supplementation on glucose and lipid metabolism and milk production of transition dairy cows

XS Wei, CJ Cai, JJ He, C Yu, F Mitloehner… - Animal Feed Science …, 2018 - Elsevier
This study aimed to evaluate the effect of supplementing biotin (BIO), nicotinamide (NAM)
and their interaction on feed intake, milk production, and energy metabolism of transition …

[HTML][HTML] Insulin signaling and insulin response in subcutaneous and retroperitoneal adipose tissue in Holstein cows during the periparturient period

Á Kenéz, L Ruda, S Dänicke, K Huber - Journal of dairy science, 2019 - Elsevier
Adipose tissue response to endocrine stimuli, such as insulin, is crucial for metabolic
adaptation at the onset of lactation in dairy cows. However, the exact molecular mechanisms …

Insulin signaling in insulin-dysregulated Icelandic horses

F Frers, J Delarocque, K Feige, K Huber… - Domestic Animal …, 2024 - Elsevier
The underlying molecular mechanisms leading to insulin dysregulation are poorly
understood in horses. Therefore, this study aimed to determine if insulin dysregulation is …

Transcriptome in Liver of Periparturient Dairy Cows Differs between Supplementation of Rumen-Protected Niacin and Rumen-Protected Nicotinamide

Y Zhang, R Li, X Du, Z Cui, X Jiang, L Wang, J Yao… - Metabolites, 2024 - mdpi.com
To investigate the difference between rumen-protected niacin (RPN) and rumen-protected
nicotinamide (RPM) in the transcriptome of genes relating to the lipid metabolism of the liver …

[HTML][HTML] Variable liver fat concentration as a proxy for body fat mobilization postpartum has minor effects on insulin-induced changes in hepatic gene expression …

C Weber, CT Schäff, U Kautzsch, S Börner… - Journal of dairy …, 2017 - Elsevier
The liver plays a central role in adaptation for energy requirements around calving, and
changes in the effects of insulin on hepatic energy metabolism contribute to metabolic …